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186198 Aldrich

tert-Butyllithium solution

1.7 M in pentane

Synonym: Lithium-2-methyl-2-propanide, t-BuLi



Related Categories 25mL Sure/Seal Reagents, Acids & Bases, Alkyl, Bases, Chemical Synthesis,
vapor density   ~3 (vs air)
concentration   1.7 M in pentane
density   0.652 g/mL at 25 °C
storage temp.   2-8°C



4×25, 100, 4×100, 800 mL in Sure/Seal™

8 L in Kilo-Lab™

The 25 mL Sure/Seal bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

View returnable container options.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Price and Availability

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Safety & Documentation

Safety Information

Signal word 
Precautionary statements 
UN 3394 4.3(4.2) / PGI
WGK Germany 
Flash Point(F) 
-56.2 °F
Flash Point(C) 
-49 °C


Certificate of Analysis

Certificate of Origin

Protocols & Articles


Acids and Bases

Acids and bases have been used by chemists for centuries, and are among the most fundamental reagents employed in synthetic organic chemistry. This Aldrich product line ranges from Brønsted and Lewis...
Chemfiles Volume 1 Article 3

MRT - Three-Stage Lithium-Organic Synthesis

Benefit from MRT & Flow Chemistry: cost & time savings, highly reliable synthesis protocol guaranteeing constant quality.
Matthias Junkers
Aldrich ChemFiles 2009, 9.4, 17.
Keywords: Continuous flow chemistry, Microreactor technology

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Molarity Calculator and Normality Calculator for Acids and Bases

The molarity calculator tool provides lab-ready directions describing how to prepare an acid or base solution of specified Molarity (M) or Normality (N) from a concentrated acid or base solution.  To...

Peer-Reviewed Papers


Set your institution to view full text papers.

Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs. Hayashi S, Ueno N, Murase A, et al. J. Enzyme Inhib. Med. Chem. 29(6), 846-67, (2014)


Beil. 4,III,2035

Fieser 1,96 / Fieser 5,79 / Fieser 7,47 / Fieser 8,70 / Fieser 9,89 / Fieser 10,76 / Fieser 11,103 / Fieser 12,100 / Fieser 13,58 / Fieser 15,64 / Fieser 16,56

Aldrich MSDS 1, 325:D / Corp MSDS 1 (1), 637:C / Structure Index 1, 482:A:2

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