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203637 Aldrich

Lithium chloride

powder, ≥99.99% trace metals basis

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Properties

Related Categories Crystal Grade Inorganics, Essential Chemicals, Lithium, Lithium Salts, Materials Science,
assay   ≥99.99% trace metals basis
form   powder
mp   605 °C(lit.)

Description

Packaging

10, 50, 100 g in poly bottle

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




Ultra-high Purity Salts

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 
1
RTECS 
OJ5950000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Acids and Bases

Acids and bases have been used by chemists for centuries, and are among the most fundamental reagents employed in synthetic organic chemistry. This Aldrich product line ranges from Brønsted and Lewis...
Chemfiles Volume 1 Article 3

Complex Hydrides: A New Category of Solid-state Lithium Fast-ion Conductors

Research and development of solid-state lithium fast-ion conductors is crucial because they can be potentially used as solid electrolytes in all-solid-state batteries, which may solve the safety and ...
Motoaki Matsuo,1 Hiroyuki Oguchi,1,2 Hideki Maekawa,2 Hitoshi Takamura,2Shin-ichi Orimo,1*
Material Matters Volume 5 Article 4
Keywords: Calorimetry, Deposition, Diffraction, Diffusion, Melting, Nuclear magnetic resonance spectroscopy, Raman spectroscopy, Search, Spectra, Spectroscopy, Substitutions, Support, X-Ray diffraction, transformation

Peer-Reviewed Papers

References

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Chemical genetics reveals a complex functional ground state of neural stem cells Diamandis, P., et. al. Nat. Chem. Biol. 3(5), 268-273, (2007)

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Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells. Acevedo KM, Opazo CM, Norrish D, et al. J. Biol. Chem. 289(16), 11007-19, (2014)

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Application of scaffolds for bone regeneration strategies: current trends and future directions. Billström GH, Blom AW, Larsson S, et al. Injury 44 Suppl 1, S28-33, (2013)

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Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds. Daniel I Perez et al J. Med. Chem. 54, 4042-56, (2011)

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Control of Hes7 expression by Tbx6, the Wnt pathway and the chemical Gsk3 inhibitor LiCl in the mouse segmentation clock. González A, Manosalva I, Liu T, et al. PLoS ONE 8(1), e53323, (2013)

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On the existence of "L-threonine formate", "L-alanine lithium chloride" and "bis L-alanine lithium chloride" crystals. Petrosyan AM, Ghazaryan VV, and Fleck M Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 105, 623-5, (2013)

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Lithium chloride attenuates cell death in oculopharyngeal muscular dystrophy by perturbing Wnt/β-catenin pathway. Abu-Baker A, Laganiere J, Gaudet R, et al. Cell Death Dis. 4, e821, (2013)

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Dose-dependent nuclear β-catenin response segregates endomesoderm along the sea star primary axis. McCauley BS, Akyar E, Saad HR, et al. Development 142(1), 207-17, (2015)

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Enhancement of Runx2 expression is potentially linked to β-catenin accumulation in canine intervertebral disc degeneration. Iwata M, Aikawa T, Hakozaki T, et al. J. Cell Physiol. 230(1), 180-90, (2015)

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Reliability of lithium dilution cardiac output in anaesthetized sheep. Axiak Flammer SM, Critchley LA, Weber A, et al. Br. J. Anaesth. 111(5), 833-9, (2013)

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Role of glycogen synthase kinase-3β in ketamine-induced developmental neuroapoptosis in rats. Liu JR, Baek C, Han XH, et al. Br. J. Anaesth. 110 Suppl 1, i3-9, (2013)

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Glucose-induced β-catenin acetylation enhances Wnt signaling in cancer. Chocarro-Calvo A, García-Martínez JM, Ardila-González S, et al. Mol. Cell. 49(3), 474-86, (2013)

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Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation. Li J, Zhang N, Huang X, et al. Cell Death Dis. 4, e832, (2013)

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Autocrine stimulation of osteoblast activity by Wnt5a in response to TNF-α in human mesenchymal stem cells. Briolay A, Lencel P, Bessueille L, et al. Biochem. Biophys. Res. Commun. 430(3), 1072-7, (2013)

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The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. Kao CY, Hsu YC, Liu JW, et al. J. Neurochem. 126(1), 4-18, (2013)

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A framework for the establishment of a cnidarian gene regulatory network for "endomesoderm" specification: the inputs of ß-catenin/TCF signaling. Röttinger E, Dahlin P, and Martindale MQ PLoS Genet. 8(12), e1003164, (2012)

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Direct observation of the hole protonation state and hole localization site in DNA-oligomers. Amitava Adhikary et al J. Am. Chem. Soc. 131, 8614-9, (2009)

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Anti-obesity effects of 3-hydroxychromone derivative, a novel small-molecule inhibitor of glycogen synthase kinase-3. Lee S, Yang WK, Song JH, et al. Biochem. Pharmacol. 85(7), 965-76, (2013)

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Kinetics and mechanism of imidazole-catalyzed acylation of cellulose in LiCl/N,N-dimethylacetamide. Nawaz H, Pires PA, and El Seoud OA Carbohydr. Polym. 92(2), 997-1005, (2013)

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Lithium chloride inhibits vascular smooth muscle cell proliferation and migration and alleviates injury-induced neointimal hyperplasia via induction of PGC-1α. Wang Z, Zhang X, Chen S, et al. PLoS ONE 8(1), e55471, (2013)

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Voltage changes in the lithium dilution cardiac output sensor after exposure to blood from horses given xylazine. Ambrisko TD and Moens Y Br. J. Anaesth. 112(2), 367-9, (2014)

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Role of olfaction in the conditioned sucrose preference of sweet-ageusic T1R3 knockout mice. Steven Zukerman et al Chem. Senses 34, 685-94, (2009)

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Nuclear factor-κB modulates osteogenesis of periodontal ligament stem cells through competition with β-catenin signaling in inflammatory microenvironments. Chen X, Hu C, Wang G, et al. Cell Death Dis. 4, e510, (2013)

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NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus. Wu Q, Zheng R, Srisai D, et al. Proc. Natl. Acad. Sci. U. S. A. 110(36), 14765-70, (2013)

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Elimination of heparin interference during microarray processing of fresh and biobank-archived blood samples. Hebels DG, van Herwijnen MH, Brauers KJ, et al. Environ. Mol. Mutagen. 55(6), 482-91, (2014)

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Real-time in vivo monitoring of circadian E-box enhancer activity: a robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock. Weger M, Weger BD, Diotel N, et al. Dev. Biol. 380(2), 259-73, (2013)

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Low-dose lithium uptake promotes longevity in humans and metazoans. Zarse K Eur. J. Nutr. 50(5), 387-9, (2011)

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Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5. Ramirez SH, Fan S, Dykstra H, et al. PLoS ONE 8(2), e55972, (2013)

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Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. Kumar A J. Virol. 82(6), 2813-20, (2008)

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The similarity between human embryonic stem cell-derived epithelial cells and ameloblast-lineage cells. Zheng LW, Linthicum L, DenBesten PK, et al. Int. J. Oral Sci. 5(1), 1-6, (2013)

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Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum. Harrison LM, Muller SH, and Spano D Neuroscience 236, 21-30, (2013)

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Are morphologic and functional consequences of status epilepticus in infant rats progressive? Kubová H and Mareš P Neuroscience 235, 232-49, (2013)

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Lithium attenuates IFN-β production and antiviral response via inhibition of TANK-binding kinase 1 kinase activity. Wang L, Zhang L, Zhao X, et al. J. Immunol. 191(8), 4392-8, (2013)

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Fractionation and structural characterization of LiCl-DMSO soluble hemicelluloses from tomato. Assor C, Quemener B, Vigouroux J, et al. Carbohydr. Polym. 94(1), 46-55, (2013)

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Lithium chloride and inhibition of glycogen synthase kinase 3β as a potential therapy for serous ovarian cancer. Novetsky AP, Thompson DM, Zighelboim I, et al. Int. J. Gynecol. Cancer 23(2), 361-6, (2013)

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Notch signaling-related therapeutic strategies with novel drugs in neuroblastoma spheroids. Ayla S, Bilir A, Soner BC, et al. J. Pediatr. Hematol. Oncol. 36(1), 37-44, (2014)

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Preferential interactions between lithium chloride and glucan chains in N,N-dimethylacetamide drive cellulose dissolution. Gross AS, Bell AT, and Chu JW J. Phys. Chem. B 117(12), 3280-6, (2013)

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Regulation of proteolytic cleavage of retinoid X receptor-α by GSK-3β. Gao W, Liu J, Hu M, et al. Carcinogenesis 34(6), 1208-15, (2013)

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Homocysteine inhibits hepatocyte proliferation via endoplasmic reticulum stress. Yu X, Lv J, Zhu Y, et al. PLoS ONE 8(1), e54265, (2013)

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β-catenin directly sequesters adipocytic and insulin sensitizing activities but not osteoblastic activity of PPARγ2 in marrow mesenchymal stem cells. Rahman S, Czernik PJ, Lu Y, et al. PLoS ONE 7(12), e51746, (2012)

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Enhanced apoptotic effects by downregulating Mcl-1: evidence for the improvement of photodynamic therapy with Celecoxib. Song J, Chen Q, and Xing D Exp. Cell Res. 319(10), 1491-504, (2013)

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Optimizations of packed sorbent and inlet temperature for large volume-direct aqueous injection-gas chromatography to determine high boiling volatile organic compounds in water. Yu B, Song Y, Han L, et al. J. Chromatogr. A 1356, 221-9, (2014)

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Bacterial maximum non-inhibitory and minimum inhibitory concentrations of different water activity depressing solutes. Cebrián G, Arroyo C, Mañas P, et al. Int. J. Food Microbiol. 188, 67-74, (2014)

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The Cdc42/Rac nucleotide exchange factor protein β1Pix (Pak-interacting exchange factor) modulates β-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of β1PIX with β-catenin. Chahdi A and Raufman JP J. Biol. Chem. 288(47), 34019-29, (2013)

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CG0009, a novel glycogen synthase kinase 3 inhibitor, induces cell death through cyclin D1 depletion in breast cancer cells. Kim HM, Kim CS, Lee JH, et al. PLoS ONE 8(4), e60383, (2013)

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Inhibition of caudal fin regeneration in Corydoras aeneus by lithium chloride. Zarnescu O, Stavri S, and Moldovan L Micron 46, 66-75, (2013)

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Lithium prevents early cytosolic calcium increase and secondary injurious calcium overload in glycolytically inhibited endothelial cells. Bosche B, Schäfer M, Graf R, et al. Biochem. Biophys. Res. Commun. 434(2), 268-72, (2013)

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Palatable food avoidance and acceptance learning with different stressors in female rats. Liang NC, Smith ME, and Moran TH Neuroscience 235, 149-58, (2013)

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Effects of transcranial focal electrical stimulation alone and associated with a sub-effective dose of diazepam on pilocarpine-induced status epilepticus and subsequent neuronal damage in rats. Besio W, Cuellar-Herrera M, Luna-Munguia H, et al. Epilepsy Behav. 28(3), 432-6, (2013)

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In-silico identification and characterization of organic and inorganic chemical stress responding genes in yeast (Saccharomyces cerevisiae). Barozai MY, Bashir F, Muzaffar S, et al. Gene 550(1), 74-80, (2014)

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Effect of lithium chloride and antineoplastic drugs on survival and cell cycle of androgen-dependent prostate cancer LNCap cells. Azimian-Zavareh V, Hossein G, and Janzamin E Indian J. Pharmacol. 44(6), 714-21, (2012)

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Lithium ameliorates open-field and elevated plus maze behaviors, and brain phospho-glycogen synthase kinase 3-beta expression in fragile X syndrome model mice. Chen X, Sun W, Pan Y, et al. Neurosciences (Riyadh.) 18(4), 356-62, (2013)

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Merck 14,5528

Fieser 1,609 / Fieser 2,246 / Fieser 4,298 / Fieser 5,677 / Fieser 13,332 / Fieser 16,194

Corp MSDS 1 (1), 2152:D / RegBook 1 (3), 3319:D / Sax 6, 1710

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