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  • 207713 - 1,3-Di-o-tolylguanidine

207713 Aldrich



Synonym: DTG



Related Categories Building Blocks, Chemical Synthesis, Guanidines, Nitrogen Compounds, Organic Building Blocks More...
assay   99%
mp   176-178 °C(lit.)
solubility   water: soluble 70 mg/mL at 20 °C
Gene Information   human ... EBP(10682)


Frequently Asked Questions

Frequently Asked Questions are available for this Product.


5, 100 g in glass bottle

General description

1,3-Di-o-tolylguanidine is a selective σ-receptor agonist. 1,3-Di-o-tolylguanidine is σ site ligand and its interaction with dopamine drugs were studied in Wistar rats and Albino Swiss mice.

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Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
What is the solubility of Product 207713, 1,3-di-o-tolylguanidine?
1,3-Di-o-tolylguanidine is soluble in water at 70 micrograms per mL at ambient temperature.
What is the nature of the biological activity of Product 207713, 1,3-di-o-tolylguanidine?
1,3-Di-o-tolylguanidine is known to be a selective ligand for the sigma site in the mammalian central nervous system. Behavioral changes, such as hypothermia, reduced pain behavior, circling behavior, and decreased locomotor activity in mice and/or rats were observed after intraperitoneal, subcutaneous, intravenous and/or intranigral injection.
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Peer-Reviewed Papers


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