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222984 Aldrich

Propranolol hydrochloride


Synonym: 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride



Related Categories Amino Alcohols, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds More...
assay   99%
mp   163-165 °C(lit.)


Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Price and Availability

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
Which enantiomer, if any, relates to Product 222984, Propranolol hydrochloride?
Although no optical rotation testing is done on this product, we would expect that this is a racemic mixture.
What is Product 222984, Propranolol hydrochloride, soluble in?
Based on our own quality control testing, we find that the product is soluble in water at 50 mg/mL. Aqueous solutions of propranolol are most stable at pH 3. Propranolol decomposes rapidly under alkaline conditions. The decomposition is often exhibited as a discoloration of the solution. According to the Merck Index, this is also expected to be soluble in alcohols. It is practically insoluble in ether, benzene and ethyl acetate.
Where can I find more information and references to the biochemical actions of Product 222984, Propranolol hydrochloride?
There is a product datasheet and an review of beta-adrenoceptors on the product webpage for similar listing, Product No. P0884. These datasheets can be reached through the following link: http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIGMA/P0884
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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Protocols & Articles


HPLC Analysis of Propranolol Enantiomers on Astec® CHIROBIOTIC® TAG

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Propranolol Enantiomers on Astec® CHIROBIOTIC® TAG
Keywords: Antihypertensives, Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers


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P0884 (±)-Propranolol hydrochloride, ≥99% (TLC), powder

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