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22600 Aldrich

Quinidine

crystallized, ≥98.0% (dried material, NT)

  • CAS Number 56-54-2

  • Empirical Formula (Hill Notation) C20H24N2O2

  • Molecular Weight 324.42

  •  Beilstein Registry Number 91866

  •  EC Number 200-279-0

  •  MDL number MFCD00135581

  •  PubChem Substance ID 24853537

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Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Catalysts, Ligands, and Reagents, Chiral Resolution Reagents, Chiral Resolving Reagents,
InChI Key   LOUPRKONTZGTKE-LHHVKLHASA-N
assay   ≥98.0% (dried material, NT)
optical activity   [α]20/D +265±5°, c = 0.8% in ethanol (dry matter)
quality   crystallized
impurities   ≤2% water
  ~10% hydroquinidine (HPLC)
mp   168-172 °C(lit.)
Gene Information   human ... ABCB1(5243), CYP2D6(1565), CYP3A4(1576), KCNH1(3756)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Cyp2d1(266684), Cyp2d2(25053), Cyp2d3(24303), Cyp2d4v1(171522)

Description

Biochem/physiol Actions

Class IA antiarrhythmic; potassium channel blocker.

Other Notes

Chiral catalyst, used e.g. in highly enantioselective [2+2] cycloadditions

Packaging

10, 50 g in poly bottle

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
VA4725000
Protocols & Articles

Articles

Cinchona Alkaloids

Cinchona alkaloids and their derivatives have proven to catalyze an astonishing array of enantioselective transformations, providing access to chiral products of high enantiopurity.1 The presence of ...
William Sommer and Daniel Weibel
Aldrich ChemFiles 2008, 8.2, 74.
Keywords: Addition reactions, Aminations, Antimicrobials, Asymmetric synthesis, Catalysis, Desymmetrizations, Dihydroxylations, Ligands, Reductive aminations

Peer-Reviewed Papers
15

References

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