232211 Aldrich

4-Pentynoic acid


Synonym: Propargylacetic acid


Related Categories Building Blocks, C1 to C5, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis,
assay   95%
bp   110 °C/30 mmHg(lit.)
mp   54-57 °C(lit.)
storage temp.   2-8°C



1, 5 g in glass bottle


Reaction with 1-bromo-1-alkynes in the presence of a Pd catalyst yields biologically active ynenol lactones.1

Used in a synthesis of a cyctotoxic macrolide by ring-closing metathesis of a bis acetylene.

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4-Pentenoic acid

≥98%, FG



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