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237655 Aldrich

(−)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane

98%

Synonym: (−)-1,4-Bis(diphenylphosphino)-1,4-dideoxy-2,3-O-isopropylidene-L-threitol, (4R,5R)-4,5-Bis(diphenylphosphino-methyl)-2,2-dimethyl-1,3-dioxolane, (4R-trans)-[(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene)]bis(diphenylphosphine), (R,R)-DIOP

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Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Catalysts, Ligands, and Reagents, DIOP, Privileged Ligands and Complexes More...
InChI Key   VCHDBLPQYJAQSQ-KYJUHHDHSA-N
assay   98%
optical activity   [α]19/D −26°, c = 2.3 in chloroform
mp   88-90 °C(lit.)
storage temp.   2-8°C

Description

Application

For the in situ preparation of chiral hydrogenation catalysts.

Packaging

1 g in glass bottle

General description

(-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane is a C2 chelating diphosphine ligand for transition metal complexes during asymmetric catalysis.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

DIOP

DIOP is one of the first chiral ligands used for asymmetric hydrogenation catalysis. DIOP can be synthesized in four simple steps from tartaric acid. Chelation with a rhodium complex generates an opt...
William Sommer and Daniel Weibel
Aldrich ChemFiles 2008, 8.2, 81.
Keywords: Asymmetric synthesis, Catalysis, Chemfiles, Hydrogenations, Ligands

DIPAMP

Rewarded by a Nobel Prize in 2001 for his pioneering work in asymmetric synthesis, Knowles was the first to develop a transition-metal chiral catalyst based on a chiral diphosphine ligand, DIPAMP, th...
William Sommer and Daniel Weibel
Aldrich ChemFiles 2008, 8.2, 81.
Keywords: Asymmetric synthesis, Catalysis, Chemfiles, Hydrogenations, Ligands, Parkinson Disease

Peer-Reviewed Papers
15

References

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