|Related Categories||Alkaloid, Building Blocks, C10, Cell Biology, Chemical Synthesis,|
Vasoactive; may have a neuromodulator function.
Biogenic amine formed from the decarboxylation of tryptophan by
25 g in poly bottle
5 g in glass bottle
Reactant for preparation of:
• Tryptamine derivatives as inhibitors against hepatitis B virus1
• Carbamoyl epipodophyllotoxins as potential antitumor agents2
• Anthranilic acid derivatives as CCK receptor antagonists3
• Brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors4
• Antispasmodic agents5
• β-carbolinium cations as new antimalarial agents6
Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry
5. Grigoryan, N. P.; et al. Hayastani Kimiakan Handes 58, 100, (2005)
Indium/TFA-catalyzed synthesis of tetracyclic [6,5,5,6] indole ring, via a tandem cycloannulation of β-oxodithioester with tryptamine. Singh TP, Bhattarcharya S, and Singh OM Org. Lett. 15(8), 1974-7, (2013)
Signal transduction and modulating pathways in tryptamine-evoked vasopressor responses of the rat isolated perfused mesenteric bed. Anwar MA, Ford WR, Herbert AA, et al. Vascul. Pharmacol. 58(1-2), 140-9, (2013)
Characterization of arylalkylamine N-acetyltransferase from silkmoth (Antheraea pernyi) and pesticidal drug design based on the baculovirus-expressed enzyme. Tsugehara T, Imai T, and Takeda M Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 157(1), 93-102, (2013)
Sequential electrophilic trifluoromethanesulfanylation-cyclization of tryptamine derivatives: synthesis of C(3)-trifluoromethanesulfanylated hexahydropyrrolo[2,3-b]indoles. Yang Y, Jiang X, and Qing FL J. Org. Chem. 77(17), 7538-47, (2012)
6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein. Valdameri G, Genoux-Bastide E, Gauthier C, et al. ChemMedChem 7(7), 1177-80, (2012)
Synthesis and photophysical properties of a supramolecular host-guest assembly constructed by fullerenes and tryptamine modified hypocrellin. Ou Z, Jin H, Gao Y, et al. J. Phys. Chem. B 116(7), 2048-58, (2012)
Electrochemical sensor based on molecularly imprinted film at polypyrrole-sulfonated graphene/hyaluronic acid-multiwalled carbon nanotubes modified electrode for determination of tryptamine. Xing X, Liu S, Yu J, et al. Biosens. Bioelectron. 31(1), 277-83, (2012)
Vasoconstrictor and vasodilator responses to tryptamine of rat-isolated perfused mesentery: comparison with tyramine and β-phenylethylamine. Anwar MA, Ford WR, Broadley KJ, et al. Br. J. Pharmacol. 165(7), 2191-202, (2012)
IR spectroscopy of monohydrated tryptamine cation: rearrangement of the intermolecular hydrogen bond induced by photoionization. Sakota K, Kouno Y, Harada S, et al. J. Chem. Phys. 137(22), 224311, (2012)
From BACE1 inhibitor to multifunctionality of tryptoline and tryptamine triazole derivatives for Alzheimer's disease. Jiaranaikulwanitch J, Govitrapong P, Fokin VV, et al. Molecules 17(7), 8312-33, (2012)
High-performance liquid chromatography with fluorescence detection and ultra-performance liquid chromatography with electrospray tandem mass spectrometry method for the determination of indoleamine neurotransmitters and their metabolites in sea lamprey plasma. Wang H, Walaszczyk EJ, Li K, et al. Anal. Chim. Acta 721, 147-53, (2012)
Serotonin accumulation in transgenic rice by over-expressing tryptophan decarboxylase results in a dark brown phenotype and stunted growth. Kanjanaphachoat P, Wei BY, Lo SF, et al. Plant Mol. Biol. 78(6), 525-43, (2012)
Tryptamine-gallic acid hybrid prevents non-steroidal anti-inflammatory drug-induced gastropathy: correction of mitochondrial dysfunction and inhibition of apoptosis in gastric mucosal cells. Pal C, Bindu S, Dey S, et al. J. Biol. Chem. 287(5), 3495-509, (2012)
FT-IR 2 (3), 3579:D / FT-IR 1 (2), 660:D / NMR-Reference 2 (2), 527:C / RegBook 1 (2), 2405:K / Sax 6, 216 / Structure Index 1, 381:B:8
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