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247952 Aldrich

2-Bromo-1,4-difluorobenzene

98%

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Properties

Related Categories Aryl, Aryl Fluorinated Building Blocks, Building Blocks, C6, Chemical Synthesis,
InChI Key   XCRCSPKQEDMVBO-UHFFFAOYSA-N
assay   98%
refractive index   n20/D 1.508(lit.)
bp   58-59 °C/20 mmHg(lit.)
mp   −31 °C(lit.)
density   1.708 g/mL at 25 °C(lit.)

Description

Packaging

5 g in glass bottle

Application

2-Bromo-1,4-difluorobenzene has been used in the preparation of 1,4-difluoroanthraquinone, a precursor to ametantrone.

General description

Lithiation of 2-bromo-1,4-difluorobenzene in the presence of lithium diisopropylamide (LDA) in THF-hexane, butyllithium in diethyl ether-hexane and butyllithium in THF-hexane has been reported.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
WGK Germany 
3
Flash Point(F) 
149 °F
Flash Point(C) 
65 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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