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250694 Aldrich

2-(Trifluoromethyl)benzaldehyde

98%

Synonym: α,α,α-Trifluoro-o-tolualdehyde

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Properties

Related Categories Aldehydes, Building Blocks, C8, Carbonyl Compounds, Chemical Synthesis,
assay   98%
refractive index   n20/D 1.466(lit.)
density   1.32 g/mL at 25 °C(lit.)

Description

Packaging

25, 100 g in glass bottle

Application

2-(Trifluoromethyl)benzaldehyde has been used in the preparation of:
• ω-(dimethylamino)-alkylethyl-4(-2-(trifluorormethyl)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates1
• methyl (E)-2-[2-[(E)-2-(2-trifluoromethylphenyl)vinyl]-phenyl]-3-methoxyacrylate via Wittig-Horner reaction2

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
WGK Germany 
3
Flash Point(F) 
141.8 °F
Flash Point(C) 
61 °C

Protocols & Articles

Peer-Reviewed Papers

References

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1. A homologous series of permanently charged 1,4-dihydropyridines: novel probes designed to localize drug binding sites on ion channels. Baindur N, Rutledge A, and Triggle DJ J. Med. Chem. 36(23), 3743-5, (1993)

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2. Phenyl beta-methoxyacrylates: a new antimalarial pharmacophore. Alzeer J, Chollet J, Heinze-Krauss I, et al. J. Med. Chem. 43(4), 560-8, (2000)

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Beil. 7,III,1013

Aldrich MSDS 1, 1769:C / Corp MSDS 1 (2), 3457:A / FT-IR 1 (2), 104:D / FT-IR 2 (2), 2522:C / FT-NMR 1 (2), 932:C / RegBook 1 (2), 1713:F / Structure Index 1, 271:D:7 / Vapor Phase 3, 1284:B

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