4-Nitroindole 97% | Sigma-Aldrich

Properties

Related Categories	Building Blocks, C7 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
assay	97%
mp	205-207 °C(lit.)

Description

Packaging

1 g in glass bottle

500 mg in glass bottle

Application

Reactant for preparation of:
• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators¹
• Meridianin derivatives as protein kinase (PKC) inhibitors and vitro antiproliferative agents²
• Anti-angiogenic agents³
• Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes⁴
• Biologically active indoles⁵
• CGRP receptor antagonists⁶
• Nucleosides⁷
• CB2 cannabinoid receptor ligands⁸

Price and Availability

Related Papers

1. Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators. Dolusic, E.; et al. J. Med. Chem. 54, 5320, (2011)

Documents

Certificate of Analysis

FT-IR Condensed Phase

FT-IR Raman

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany	3

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Indoles

Sigma-Aldrich is proud to offer a new series of ChemFiles—called Privileged Structures, to our Drug Discovery and Organic Synthesis customers. Each piece will highlight a specific motif, selected app...
Chemfiles Volume 4 Article 8
Keywords: Building blocks, Cardiovascular, Diabetes, Diseases, Drug discovery, Medicinal chemistry, Organic synthesis, Respiratory