Harmine

Papers

The selectivity of protein kinase inhibitors: a further update Bain, J., et al. Biochem. J. 408, 297-315, (2007)

---

Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Johannes Kornhuber et al J. Med. Chem. 51, 219-37, (2008)

---

The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors. Galarreta, B., C.; et al. Bioorg. Med. Chem. 16, 6689, (2008)

---

Synthesis and in vitro cytotoxic evaluation of novel 3,4,5-trimethoxyphenyl substituted beta-carboline derivatives. Qifeng Wu et al Eur. J. Med. Chem. 44, 533-40, (2009)

---

A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency. Jiawang Liu et al J. Med. Chem. 53, 3106-16, (2010)

---

A repurposing strategy identifies novel synergistic inhibitors of Plasmodium falciparum heat shock protein 90. Dea Shahinas et al J. Med. Chem. 53, 3552-7, (2010)

---

Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds. Shinya Oishi et al J. Med. Chem. 53, 5054-8, (2010)

---

Proposed structural basis of interaction of piperine and related compounds with monoamine oxidases. Taufiq Rahman et al Bioorg. Med. Chem. Lett. 20, 537-40, (2010)

---

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing. Mansour Debdab et al J. Med. Chem. 54, 4172-86, (2011)

---

Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators. Dolusic, E.; et al. J. Med. Chem. 54, 5320, (2011)

---

Synthesis and evaluation of ?-carboline derivatives as potential monoamine oxidase inhibitors. J Reniers et al Bioorg. Med. Chem. 19, 134-44, (2011)

---

A class of novel N-(1-methyl-?-carboline-3-carbonyl)-N'-(aminoacid-acyl)-hydrazines: aromatization leaded design, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis. Chunyu Li et al Eur. J. Med. Chem. 46, 5598-608, (2011)

---

Catalysis by molecular iodine: A rapid synthesis of 1,8-dioxo-octahydroxanthenes and their evaluation as potential anticancer agents. Naveen Mulakayala et al Bioorg. Med. Chem. Lett. 22, 2186-91, (2012)

---

Ultrasound mediated catalyst free synthesis of 6H-1-benzopyrano[4,3-b]quinolin-6-ones leading to novel quinoline derivatives: their evaluation as potential anti-cancer agents. Naveen Mulakayala et al Bioorg. Med. Chem. 20, 759-68, (2012)

---

Merck 14,4616

Beil. 23,V,12,237

Corp MSDS 1 (1), 1810:C / FT-IR 2 (3), 3616:B / FT-NMR 1 (3), 166:B / RegBook 1 (2), 2427:I / Sax 6, 1781 / Sigma FT-IR 1 (2), 600:B / Structure Index 1, 385:C:2