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289132 Aldrich

Urea hydrogen peroxide


Synonym: Carbamide Per hydrate, Carbamide peroxide, Hydrogen peroxide–Urea adduct, Percarbamide, Urea hydrogen peroxide



Related Categories Chemical Synthesis, Oxidizing Agents, Peroxides, Synthetic Reagents
vapor pressure   23.3 mmHg ( 30 °C)
assay   97%
mp   90-93 °C(lit.)
storage temp.   2-8°C



Peroxide used with N-halosuccinimides in an efficient α-halogentation of carbonyl compounds.1 Used with methyltrioxorhenium (412910) in a mild oxidation of imines to nitrones.2 Also used to oxidize iodoarenes to hypervalent iodine compounds.3


100, 250 g in poly bottle

5 g in glass bottle

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Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
UN 1511 8(5.1) / PGIII
WGK Germany 

Protocols & Articles

Peer-Reviewed Papers


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1. Synth. Commun. 37, 87, (2007)

2. Catalytic oxidation of imines based on methyltrioxorhenium/urea hydrogen peroxide: a mild and easy chemo- and regioselective entry to nitrones. Org. Lett. 9, 473, (2007)


3. Synthesis, 3153, (2006)

Indole peroxygenase activity of indoleamine 2,3-dioxygenase. Kuo HH and Mauk AG Proc. Natl. Acad. Sci. U. S. A. 109(35), 13966-71, (2012)


The timing and operational management of the variables of bleaching in cases of rehabilitation in the esthetic field. Sibilla P, Cogo E, Turrini R, et al. Int. J. Esthet. Dent. 9(3), 436-45, (2014)


Minimally invasive rehabilitation of a patient with amelogenesis imperfecta. Büchi D, Fehmer V, Sailer I, et al. Int. J. Esthet. Dent. 9(2), 134-45, (2014)


Effects of dental bleaching on the color, translucency and fluorescence properties of enamel and dentin. Caneppele TM, Borges AB, and Torres CR Eur. J. Esthet. Dent. 8(2), 200-12, (2013)


Combining enamel microabrasion and dental bleaching: recovering smile aesthetics. Machado LS, Sundfeld Neto D, de Oliveira GB, et al. Dent. Today 32(3), 110-1, (2013)


Value for your profession. Optimize whitening success, and grow your practice. Stewart CB and Healthcare PO Tex. Dent. J. 129(11), 1222-5, (2012)


A comparative study of different bleaching agents on the morphology of human enamel: an in vitro SEM study. Uthappa R, Suprith ML, Bhandary S, et al. J. Contemp. Dent. Pract. 13(6), 756-9, (2012)


Effect of chemical activation of 10% carbamide peroxide gel in tooth bleaching. Batista GR, Arantes PT, Attin T, et al. Eur. J. Esthet. Dent. 8(1), 104-17, (2013)


A minimally invasive smile restoration. A case report describing a multitechnique approach over time. Sundfeld RH, de Oliveira FG, Toseto RM, et al. Dent. Today 31(12), 86-9, (2012)


Effects of toothbrushing with fluoride abrasive and whitening dentifrices on both unbleached and bleached human enamel surface in terms of roughness and hardness: an in vitro study. Bolay S, Cakir FY, and Gurgan S J. Contemp. Dent. Pract. 13(5), 584-9, (2012)


Effect of four over-the-counter tooth-whitening products on enamel microhardness. Majeed A, Grobler SR, Moola MH, et al. SADJ 66(9), 412-5, (2011)


Functional magnetic resonance imaging: focus localization. Jackson GD, Badawy R, and Gotman J Handb. Clin. Neurol. 107, 369-85, (2012)


Analysis of surface roughness of human enamel exposed to bleaching agent and submitted to brushing. Pachaly R and Pozzobon RT Acta Odontol. Latinoam. 25(1), 59-66, (2012)


Occurrence of sensitivity during at-home and in-office tooth bleaching therapies with or without use of light sources. de Almeida LC, Costa CA, Riehl H, et al. Acta Odontol. Latinoam. 25(1), 3-8, (2012)


Surface morphological changes in human enamel following bleaching: an in vitro scanning electron microscopic study. Rajesh AG, Ranganath LM, Kumar KS, et al. J. Contemp. Dent. Pract. 13(3), 405-15, (2012)


Esthetic rehabilitation of anterior discolored teeth with lithium disilicate all-ceramic restorations. Prevedello GC, Vieira M, Furuse AY, et al. Gen. Dent. 60(4), e274-8, (2012)


Effect of 10% and 15% carbamide peroxide on fracture toughness of human dentin in situ. Tam LE, Bahrami P, Oguienko O, et al. Oper. Dent. 38(2), 142-50, (2013)


Comparative clinical study of the effectiveness of different dental bleaching methods - two year follow-up. Mondelli RF, Azevedo JF, Francisconi AC, et al. J. Appl. Oral Sci. 20(4), 435-43, (2012)


Long-term efficacy of in-office and at-home bleaching: a 2-year double-blind randomized clinical trial. Tay LY, Kose C, Herrera DR, et al. Am. J. Dent. 25(4), 199-204, (2012)


A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens. Xiaobin Tang et al J. Immunol. 182, 5446-52, (2009)


Efficiency of invasive mechanical ventilation during sleep in Duchenne muscular dystrophy. Nardi J, Prigent H, Garnier B, et al. Sleep Med. 13(8), 1056-65, (2012)


Effect of delaying toothbrushing during bleaching on enamel surface roughness: an in vitro study. Navimipour EJ, Mohammadi N, Mostafazadeh S, et al. Oper. Dent. 38(2), 218-25, (2013)


Efficacy of mouth rinses and toothpaste on tooth whitening. Torres CR, Perote LC, Gutierrez NC, et al. Oper. Dent. 38(1), 57-62, (2013)


Effect of 15% carbamide peroxide bleaching gel on color stability of giomer and microfilled composite resin: an in vitro comparison. Mohammadi N, Kimyai S, Abed-Kahnamoii M, et al. Med. Oral Patol. Oral Cir. Bucal 17(6), e1082-8, (2012)


Influence of fluoride-containing adhesives and bleaching agents on enamel bond strength. Cavalli V, Liporoni PC, Rego MA, et al. Braz. Oral Res. 26(6), 536-42, (2012)


Secondary caries inhibition promoted by adhesive systems and bleaching agents with fluoride. Cavalli V, Cardoso Cde A, Zandonadi Fde A, et al. Am. J. Dent. 25(3), 141-5, (2012)


Ion release from a composite resin after exposure to different 10% carbamide peroxide bleaching agents. Bueno RP, Viaro PS, Nascimento PC, et al. J. Appl. Oral Sci. 20(3), 335-9, (2012)


DNA-damaging effects of dental bleaching agents. Pligina KL, Rodina IA, Shevchenko TV, et al. Bull. Exp. Biol. Med. 153(1), 57-60, (2012)


Merck 14,1782

Beil. 3,IV,94

Fieser 16,379 / Fieser 17,148

Corp MSDS 1 (2), 3579:B / FT-IR 2 (1), 1358:A / RegBook 1 (1), 939:G / Sax 6, 1551 / Structure Index 1, 146:B:2

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