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320129 Aldrich

Acetyl chloride

reagent grade, 98%

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Properties

Related Categories Acid Halides, Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks More...
grade   reagent grade
vapor density   2.7 (vs air)
vapor pressure   11.69 psi ( 20 °C)
  32.33 psi ( 55 °C)
InChI Key   WETWJCDKMRHUPV-UHFFFAOYSA-N
assay   98%
autoignition temp.   1353 °F
expl. lim.   19 %
refractive index   n20/D 1.389(lit.)
bp   52 °C(lit.)
mp   −112 °C(lit.)
density   1.104 g/mL at 25 °C(lit.)

Description

Packaging

1 kg in PVC-coated bottle

General description

Acetyl chloride undergoes reaction with decalin and aluminum trichloride to afford a tricyclic enol ether. It promotes the cyclopropanation of alkene with dibromomethane or diiodomethane in the presence of Zn dust and copper chloride in ether. Friedel-Crafts reaction of acetyl chloride with benzene in the presence of MCl3 (M = Al or Fe) in the ionic liquid 1-butyl-3-methylimidazolium chloride affords MCl3 adducts of the acetyl chloride, the acetylium ion [CH3CO]+[MCl4]- and the MCl3 adduct of acetophenone.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
Reacts violently with water.
RIDADR 
UN 1717 8(3) / PGII
WGK Germany 
1
RTECS 
AO6390000
Flash Point(F) 
41 °F
Flash Point(C) 
5 °C
Protocols & Articles

Articles

Friedel–Crafts Acylation

The Friedel–Crafts acylation is the reaction of an arene with acyl chlorides or anhydrides using a strong Lewis acid catalyst. This reaction proceeds via electrophilic aromatic substitution to form m...
Keywords: Acylations, Catalysis, Electrophilic aromatic substitution, Microwave synthesis, Substitutions

Peer-Reviewed Papers
15

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