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326143 Aldrich

Iodine

≥99.99% trace metals basis

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Properties

Related Categories C-X Bond Formation (Halogen), Chemical Synthesis, Electronic Chemicals, Iodination, Materials Science,
vapor density   9 (vs air)
vapor pressure   0.31 mmHg ( 25 °C)
  1 mmHg ( 38.7 °C)
assay   ≥99.99% trace metals basis
resistivity   1.3E15 μΩ-cm
bp   184 °C(lit.)
mp   113 °C(lit.)

Description

Packaging

10, 100 g in glass bottle

Price and Availability

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Precautionary statements 
Target organs 
Thyroid.
Personal Protective Equipment 
RIDADR 
UN 1759 8/PG 2
WGK Germany 
2
RTECS 
NN1575000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Water Content in Iodine Using Karl Fischer Titration

The iodine sample can not be introduced directly into the titration vessel because it is a component of the KF reaction. We chose the following procedure: 1. Determination of the iodine content with ...
Keywords: Titrations

Peer-Reviewed Papers

References

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Evidence-based interventions for improvement of maternal and child nutrition: what can be done and at what cost? Bhutta ZA, Das JK, Rizvi A, et al. Lancet 382(9890), 452-77, (2013)

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Maternal and child undernutrition and overweight in low-income and middle-income countries. Black RE, Victora CG, Walker SP, et al. Lancet 382(9890), 427-51, (2013)

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Assessment of iodine nutrition in populations: past, present, and future. Zimmermann MB and Andersson M Nutr. Rev. 70(10), 553-70, (2012)

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Global iodine nutrition: Where do we stand in 2013? Pearce EN, Andersson M, and Zimmermann MB Thyroid 23(5), 523-8, (2013)

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Iodine and mental development of children 5 years old and under: a systematic review and meta-analysis. Bougma K, Aboud FE, Harding KB, et al. Nutrients 5(4), 1384-416, (2013)

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The adverse effects of mild-to-moderate iodine deficiency during pregnancy and childhood: a review. Zimmermann MB Thyroid 17(9), 829-35, (2007)

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Hypothyroxinemia and TPO-antibody positivity are risk factors for premature delivery: the generation R study. Korevaar TI, Schalekamp-Timmermans S, de Rijke YB, et al. J. Clin. Endocrinol. Metab. 98(11), 4382-90, (2013)

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Exposure to pyrethroids insecticides and serum levels of thyroid-related measures in pregnant women. Zhang J, Hisada A, Yoshinaga J, et al. Environ. Res. 127, 16-21, (2013)

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Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC). Bath SC, Steer CD, Golding J, et al. Lancet 382(9889), 331-7, (2013)

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Effect of iodine supplementation in pregnancy on child development and other clinical outcomes: a systematic review of randomized controlled trials. Zhou SJ, Anderson AJ, Gibson RA, et al. Am. J. Clin. Nutr. 98(5), 1241-54, (2013)

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Iodine deficiency and excess in children: worldwide status in 2013. Zimmermann MB Endocr. Pract. 19(5), 839-46, (2013)

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Energy characterisation of ultrasonic systems for industrial processes. Al-Juboori RA, Yusaf T, Bowtell L, et al. Ultrasonics 57, 18-30, (2015)

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Delayed adverse reactions to the parenteral administration of iodinated contrast media. Egbert RE, De Cecco CN, Schoepf UJ, et al. AJR Am. J. Roentgenol. 203(6), 1163-70, (2014)

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Iodine excretion has decreased in Denmark between 2004 and 2010--the importance of iodine content in milk. Rasmussen LB, Carlé A, Jørgensen T, et al. Br. J. Nutr. 112(12), 1993-2001, (2014)

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Clinical challenges Q&A. 2. A sweaty face. Scully C and Malamos D Dent. Update 41(6), 556, (2014)

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Preoperative contrast-enhanced computerized tomography should not delay radioiodine ablation in differentiated thyroid carcinoma patients. Mishra A, Pradhan PK, Gambhir S, et al. J. Surg. Res. 193(2), 731-7, (2015)

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[Euthyroid struma with a thyroid nodule. Is the combination of L-thyroxine and iodine effective here?]. Füessl HS and Stiefelhagen P MMW Fortschr. Med. 156(8), 17, (2014)

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CT angiography of the neck: value of contrast medium dose reduction with low tube voltage and high tube current in a 64-detector row CT. Xia W, Wu JT, Yin XR, et al. Clin. Radiol. 69(4), e183-9, (2014)

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[Iodinated contrast media and iodine allergy: myth or reality?]. Meunier B, Joskin J, Damas F, et al. Rev. Med. Liege. 68(9), 465-9, (2013)

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[Application of iodine metabolism analysis methods in thyroid diseases]. Han JH and Qiu L Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 35(4), 369-72, (2013)

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[The increase of non-cancerous thyroid tissue in children and adolescents operated for papillary thyroid cancer: related factors]. Fridman MV, Kras'ko OV, Man'kovskaia SV, et al. Vopr. Onkol. 59(2), 121-5, (2013)

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[Application of herbal medicine alba in treatment of patients with the pathology of thyroid]. Kiselëva IA, Tëplaia EV, and Kaminskiĭ AV Lik. Sprava (8), 116-9, (2012)

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Immediate and delayed hypersensitivity reactions to intravascular iodine based radiocontrast media -- an update. Bumbăcea RS, Petruţescu B, Bumbăcea D, et al. Pneumologia 62(1), 47-51, (2013)

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[Iodine supply and thyroid function in the group of healthy pregnant women living in Warsaw]. Krasnodebska-Kiljańska M, Kondracka A, Bartoszewicz Z, et al. Pol. Merkur. Lekarski 34(202), 200-4, (2013)

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Maternal iodine deficiency may threaten children's IQ. BMJ 346, f3400, (2013)

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Comparison of pasteurized whole milk, UHT whole milk, water, and diluted iodine contrast as computed tomographic enteric contrasts. Apisarnthanarak P, Tiangpug T, Pongpornsup S, et al. J. Med. Assoc. Thai. 96(4), 467-76, (2013)

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[Iodine and thyroid gland with or without nuclear catastrophe]. Dilas LT, Bajkin I, Icin T, et al. Med. Pregl. 65(11-12), 489-95, (2012)

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The implications of iodine and its supplementation during pregnancy in fetal brain development. Puig-Domingo M and Vila L Curr. Clin. Pharmacol. 8(2), 97-109, (2013)

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Antiseptics, iodine, povidone iodine and traumatic wound cleansing. Khan MN and Naqvi AH J. Tissue Viability 16(4), 6-10, (2006)

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Spectrophotometric determination of drugs with iodine. Karuna T, et al. J. Sci. Ind. Res. 65(10), 808, (2006)

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Mild iodine deficiency during pregnancy is associated with reduced educational outcomes in the offspring: 9-year follow-up of the gestational iodine cohort. Hynes KL, Otahal P, Hay I, et al. J. Clin. Endocrinol. Metab. 98(5), 1954-62, (2013)

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Biomarkers of nutrition for development--iodine review. Rohner F, Zimmermann M, Jooste P, et al. J. Nutr. 144(8), 1322S-1342S, (2014)

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Iodine fortification may influence the age-related change in thyroid volume: a longitudinal population-based study (DanThyr). Krejbjerg A, Bjergved L, Pedersen IB, et al. Eur. J. Endocrinol. 170(4), 507-17, (2014)

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Catalyst-controlled highly selective coupling and oxygenation of olefins: a direct approach to alcohols, ketones, and diketones. Su Y, Sun X, Wu G, et al. Angew. Chem. Int. Ed. Engl. 52(37), 9808-12, (2013)

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Longitudinal trends in thyroid function in relation to iodine intake: ongoing changes of thyroid function despite adequate current iodine status. van de Ven AC, Netea-Maier RT, Ross HA, et al. Eur. J. Endocrinol. 170(1), 49-54, (2014)

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Thyroid status and 6-year mortality in elderly people living in a mildly iodine-deficient area: the aging in the Chianti Area Study. Ceresini G, Ceda GP, Lauretani F, et al. J. Am. Geriatr. Soc. 61(6), 868-74, (2013)

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Structural variability between starch granules in wild type and in ae high-amylose mutant maize kernels. Liu D, Parker ML, Wellner N, et al. Carbohydr. Polym. 97(2), 458-68, (2013)

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Iodine deficiency in pregnant women living in the South East of the UK: the influence of diet and nutritional supplements on iodine status. Bath SC, Walter A, Taylor A, et al. Br. J. Nutr. 111(9), 1622-31, (2014)

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EURRECA-Estimating iodine requirements for deriving dietary reference values. Ristić-Medić D, Novaković R, Glibetić M, et al. Crit. Rev. Food Sci. Nutr 53(10), 1051-63, (2013)

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Iodine contributes to thyroid autoimmunity in humans by unmasking a cryptic epitope on thyroglobulin. Latrofa F, Fiore E, Rago T, et al. J. Clin. Endocrinol. Metab. 98(11), E1768-74, (2013)

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Need for coordinated programs to improve global health by optimizing salt and iodine intake. Campbell NR, Dary O, Cappuccio FP, et al. Rev. Panam. Salud Publica. 32(4), 281-6, (2012)

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Ultrasound-assisted enzymatic hydrolysis for iodinated amino acid extraction from edible seaweed before reversed-phase high performance liquid chromatography-inductively coupled plasma-mass spectrometry. Romarís-Hortas V, Bermejo-Barrera P, and Moreda-Piñeiro A J. Chromatogr. A 1309, 33-40, (2013)

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The synthesis of benzo[f]isoindole-1,3-dicarboxylates via an i2-induced 1,3-dipolar cycloaddition reaction. Li YJ, Huang HM, Dong HQ, et al. J. Org. Chem. 78(18), 9424-30, (2013)

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Design of the South East Asian Nutrition Survey (SEANUTS): a four-country multistage cluster design study. Schaafsma A, Deurenberg P, Calame W, et al. Br. J. Nutr. 110 Suppl 3, S2-10, (2013)

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Urinary excretion of sodium, potassium, and chloride, but not iodine, varies by timing of collection in a 24-hour calibration study. Wang CY, Cogswell ME, Loria CM, et al. J. Nutr. 143(8), 1276-82, (2013)

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Th17 cell plays a role in the pathogenesis of Hashimoto's thyroiditis in patients. Li D, Cai W, Gu R, et al. Clin. Immunol. 149(3), 411-20, (2013)

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Therapy of endocrine disease: Impact of iodine supplementation in mild-to-moderate iodine deficiency: systematic review and meta-analysis. Taylor PN, Okosieme OE, Dayan CM, et al. Eur. J. Endocrinol. 170(1), R1-R15, (2014)

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Race-ethnicity is related to biomarkers of iron and iodine status after adjusting for sociodemographic and lifestyle variables in NHANES 2003-2006. Pfeiffer CM, Sternberg MR, Caldwell KL, et al. J. Nutr. 143(6), 977S-85S, (2013)

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Iodine deficiency in the U.K.: an overlooked cause of impaired neurodevelopment? Bath SC and Rayman MP Proc. Nutr. Soc. 72(2), 226-35, (2013)

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Accuracy of contrast-enhanced dual-energy MDCT for the assessment of iodine uptake in renal lesions. Mileto A, Marin D, Ramirez-Giraldo JC, et al. AJR Am. J. Roentgenol. 202(5), W466-74, (2014)

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The challenges in assessing contrast-induced nephropathy: where are we now? Davenport MS, Cohan RH, Khalatbari S, et al. AJR Am. J. Roentgenol. 202(4), 784-9, (2014)

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Intakes of dairy products and dietary supplements are positively associated with iodine status among U.S. children. Perrine CG, Sullivan KM, Flores R, et al. J. Nutr. 143(7), 1155-60, (2013)

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The prevalence of using iodine-containing supplements is low among reproductive-age women, NHANES 1999-2006. Gahche JJ, Bailey RL, Mirel LB, et al. J. Nutr. 143(6), 872-7, (2013)

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Precision of iodine quantification in hepatic CT: effects of iterative reconstruction with various imaging parameters. Chen B, Marin D, Richard S, et al. AJR Am. J. Roentgenol. 200(5), W475-82, (2013)

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The extrathyronine actions of iodine as antioxidant, apoptotic, and differentiation factor in various tissues. Aceves C, Anguiano B, and Delgado G Thyroid 23(8), 938-46, (2013)

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Topical contrast agents to improve soft-tissue contrast in the upper airway using cone beam CT: a pilot study. Alsufyani NA, Noga ML, Finlay WH, et al. Dentomaxillofac. Radiol. 42(7), 20130022, (2013)

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Solvent-dependent molecular structure of ionic species directly measured by ultrafast x-ray solution scattering. Kim KH, Lee JH, Kim J, et al. Phys. Rev. Lett. 110(16), 165505, (2013)

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Improved iodine status in Tasmanian schoolchildren after fortification of bread: a recipe for national success. DePaoli KM, Seal JA, Burgess JR, et al. Med. J. Aust. 198(9), 492-4, (2013)

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Long-term exposure to excessive iodine from water is associated with thyroid dysfunction in children. Sang Z, Chen W, Shen J, et al. J. Nutr. 143(12), 2038-43, (2013)

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A theoretical study on the formation of iodine oxide aggregates and monohydrates. Gálvez O, Gómez Martín JC, Gómez PC, et al. Phys. Chem. Chem. Phys. 15(37), 15572-83, (2013)

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History of U.S. iodine fortification and supplementation. Leung AM, Braverman LE, and Pearce EN Nutrients 4(11), 1740-6, (2012)

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Skin test-positive immediate hypersensitivity reaction to iodinated contrast media: the role of controlled challenge testing. Prieto-García A, Tomás M, Pineda R, et al. J. Investig. Allergol. Clin. Immunol. 23(3), 183-9, (2013)

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Synthesis and structure of conjugated molecules with the benzofulvene core. Martinelli C, Cardone A, Pinto V, et al. Org. Lett. 16(13), 3424-7, (2014)

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Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates. Chen JJ, et al. PLoS ONE 4(3), e4949, (2009)

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Goiter and other iodine deficiency disorders: A systematic review of epidemiological studies to deconstruct the complex web. Kotwal A, Priya R, and Qadeer I Arch. Med. Res. 38(1), 1-14, (2007)

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Evidence needed to inform the next dietary reference intakes for iodine. Trumbo PR Adv. Nutr. 4(6), 718-22, (2013)

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Total iodine in infant formula and nutritional products by inductively coupled plasma/mass spectrometry: First Action 2012.14. Pacquette LH, Levenson AM, Thompson JJ, et al. J. AOAC Int. 96(4), 798-801, (2013)

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Urinary iodine excretion after contrast computed tomography scan: implications for radioactive iodine use. Nimmons GL, Funk GF, Graham MM, et al. JAMA Otolaryngol. Head Neck Surg. 139(5), 479-82, (2013)

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Monitoring and effects of iodine deficiency in pregnancy: still an unsolved problem? Pearce EN Eur. J. Clin. Nutr. 67(5), 481-4, (2013)

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The treatment of Graves' disease in children. Rivkees SA J. Pediatr. Endocrinol. Metab. 19(9), 1095-111, (2006)

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Iodine deficiency in Egyptian autistic children and their mothers: relation to disease severity. Hamza RT, Hewedi DH, and Sallam MT Arch. Med. Res. 44(7), 555-61, (2013)

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When to Order a Contrast-Enhanced CT. Rawson JV and Pelletier AL Am. Fam. Physician 88(5), 312-6, (2013)

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Iodine quantification with dual-energy CT: phantom study and preliminary experience with VX2 residual tumour in rabbits after radiofrequency ablation. Li Y, Shi G, Wang S, et al. Br. J. Radiol. 86(1029), 20130143, (2013)

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Induction of thyroid neoplasm following plant medicine marine algae (sargassum): a rare case and review of the literature. Zhu G, Musumeci F, and Byrne P Curr. Pharm. Biotechnol. 14(9), 859-63, (2013)

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Control of iodine-deficiency disorders following universal salt iodization in Shenzhen, China, 1997-2011. Huang W, Peng C, Huang H, et al. Food Nutr. Bull. 34(3), 331-7, (2013)

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Bioavailability of iodine in the UK-Peak District environment and its human bioaccessibility: an assessment of the causes of historical goitre in this area. Mehra A, Saikat SQ, and Carter JE Environ. Monit. Assess. 186(2), 987-99, (2014)

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[Iodine and thyroid: what a clinic should know]. Santana Lopes M, Jácome de Castro J, Marcelino M, et al. Acta Med. Port. 25(3), 174-8, (2012)

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Hormonogenic donor Tyr2522 of bovine thyroglobulin. Insight into preferential T3 formation at thyroglobulin carboxyl terminus at low iodination level. Cetrangolo GP, Arcaro A, Lepore A, et al. Biochem. Biophys. Res. Commun. 450(1), 488-93, (2014)

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Comparative study of disinfectants for use in low-cost gravity driven household water purifiers. Patil RA, Kausley SB, Balkunde PL, et al. J. Water Health 11(3), 443-56, (2013)

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Production of granular activated carbon from food-processing wastes (walnut shells and jujube seeds) and its adsorptive properties. Bae W, Kim J, and Chung J J. Air Waste Manag. Assoc. 64(8), 879-86, (2014)

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Hypothyroidism: causes, killers, and life-saving treatments. Dubbs SB and Spangler R Emerg. Med. Clin. North Am. 32(2), 303-17, (2014)

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Medical management of a potentially toxic accidental trialkylamine ingestion during spaceflight. Blue RS, Hudson JC, Rieders MF, et al. Aviat. Space. Environ. Med. 84(10), 1100-4, (2013)

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Iodine status after iodized salt supplementation in schoolchildren of eastern Nepal. Nepal AK, Khatiwada S, Shakya PR, et al. Southeast Asian J. Trop. Med. Public Health 44(6), 1072-8, (2013)

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[Factors associated with nutritional status of iodine in Mexican preschool children]. López Rodríguez G, Galván M, Silva Maldonado I, et al. Gac. Med. Mex. 149(2), 161-7, (2013)

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[Epidemiological parameters in the evaluation of endemic goiter in the Republic of North Ossetia-Alania]. Tsabolova ZT, Zangieva OD, and Basieva OO Ter. Arkh. 85(5), 73-7, (2013)

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[Hyperthyroidism after iodine-containing contrast agent administration]. Żach M, Kryjan K, Ambroziak U, et al. Kardiol. Pol. 71(7), 752-6, (2013)

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Iodine deficiency, pollutant chemicals, and the thyroid: new information on an old problem. Pediatrics 133(6), 1163-6, (2014)

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Hypothyroidism is still prevalent in India despite promotion of iodised salt, study shows. Bagcchi S BMJ 347, f7693, (2013)

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Reinforcing the iodine message for pregnant women in Australia. Charlton KE and Eastman CJ Med. J. Aust. 199(10), 660, (2013)

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Even mild iodine deficiency during gestation may impair brain function in children. Mitka M JAMA 309(23), 2428, (2013)

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Iodine and pregnancy: a call to action. Stagnaro-Green A and Pearce EN Lancet 382(9889), 292-3, (2013)

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Study links iodine deficiency in pregnancy with poor cognitive outcomes in children. Loewenthal L BMJ 346, f3365, (2013)

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Regional centers: added value to poison center surveillance. Durigon M and Kosatsky T Clin. Toxicol. (Phila.) 51(6), 521, (2013)

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DRESS syndrome involving 2 unrelated substances: imipenem and iodinated contrast media. Macías EM, Muñoz-Bellido FJ, Velasco A, et al. J. Investig. Allergol. Clin. Immunol. 23(1), 56-7, (2013)

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Merck 14,5014

Fieser 1,495 / Fieser 2,220 / Fieser 2,200 / Fieser 3,159 / Fieser 4,258 / Fieser 5,346 / Fieser 6,293 / Fieser 7,179 / Fieser 8,256 / Fieser 9,248 / Fieser 10,210 / Fieser 11,261 / Fieser 11,201 / Fieser 12,253 / Fieser 13,148 / Fieser 14,181 / Fieser 15,172 / Fieser 16,182 / Fieser 17,153

Aldrich MSDS 1, 1089:B / Corp MSDS 1 (1), 1988:D / RegBook 1 (3), 3221:H / Sax 6, 1616

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