EMAIL THIS PAGE TO A FRIEND

328464 Aldrich

2-Azetidinone

98%

Synonym: β-Propiolactam, 2-Azacyclobutanone

  • CAS Number 930-21-2

  • Empirical Formula (Hill Notation) C3H5NO

  • Molecular Weight 71.08

  •  Beilstein Registry Number 104563

  •  MDL number MFCD00013328

  •  PubChem Substance ID 24859374

  • Popular Documents:  FTNMR (PDF)  

Purchase

Properties

Related Categories Building Blocks, Carbonyl Compounds, Chemical Synthesis, Lactams, Organic Building Blocks More...
assay   98%
bp   106 °C/15 mmHg(lit.)
mp   74-76 °C(lit.)
solubility   chloroform: very soluble(lit.)
  ethanol: very slightly soluble(lit.)
  water: very soluble(lit.)
storage temp.   2-8°C

Description

Packaging

1, 5 g in glass bottle

Application

2-Azetidinone was used in synthesis of optically pure densely functionalized γ-lactams.1

General description

2-Azetidinone is an unsubstituted four membered lactam.2 2-Azetidinone is the fundamental building block of β-lactam antibiotics.3 X-ray photoelectron spectra of 2-azetidinone was investigated.3 2-Azetidinone undergoes hydrolysis with aqueous alkali to yield β-alanine.2

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
Hazard Codes (Europe) 
C
Risk Statements (Europe) 
34
Safety Statements (Europe) 
26-36/37/39-45
RIDADR 
UN 3263 8 / PGII
WGK Germany 
3

Protocols & Articles

Peer-Reviewed Papers

References

Set your institution to view full text papers.

1. Synthesis of optically pure highly functionalized gamma-lactams via 2-azetidinone-tethered iminophosphoranes. Alcaide B, Almendros P, and Alonso JM J. Org. Chem. 69(3), 993-6, (2004)

Loading...


2. 2-Azetidinone (ß-propiolactam) Holley RW and Holley AD. J. Am. Chem. Soc. 71(6), 2129-31, (1949)

3. Photoelectron spectra of some antibiotic building blocks: 2-azetidinone and thiazolidine-carboxylic acid. Ahmed M, Ganesan A, Wang F, et al. J. Phys. Chem. A 116(33), 8653-60, (2012)

Loading...


Beil. 21,V,6,312

FT-IR 2 (1), 1336:B / FT-NMR 1 (1), 1285:A / RegBook 1 (1), 923:A / Structure Index 1, 143:B:3

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?