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332607 Aldrich

(2-Hydroxypropyl)-β-cyclodextrin

average Mw ~1,460

Synonym: (2-Hydroxypropyl)-beta-cyclodextrin

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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Capillary Electrophoresis, Chelation/Complexation Compounds, Chemical Synthesis,
optical activity   [α]25/D +135°, c = 1 in H2O (typical)
mol wt   average Mw ~1,460
extent of labeling   0.8 molar substitution
mp   267 °C (dec.)

Description

Application

The solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice.

Packaging

5, 25, 100, 500 g in glass bottle

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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