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336467 Aldrich

Benz[cd]indol-2(1H)-one

technical grade

Synonym: NSC 25094

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Properties

Related Categories Building Blocks, C11, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
grade   technical grade
InChI Key   GPYLCFQEKPUWLD-UHFFFAOYSA-N
mp   173-178 °C(lit.)
solubility   methanol: soluble25 mg/mL, clear, yellow to brown

Description

Packaging

5 g in glass bottle

Application

• Reactant in photo-Fries rearrangement
• Reactant in preparation of potential antitumor agents
• Reactant in synthesis of inhibitors of thymidylate synthase

Benz[cd]indol-2(1H)-one was used in the synthesis of 2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide analog, novel Mycobacterium protein tyrosine phosphatase B (mPTPB) inhibitor.

General description

Benz[cd]indol-2(1H)-one is also referred as naphtholactam.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
DE3202000
Protocols & Articles

Articles

Fries Rearrangement

The Fries rearrangement reaction is an organic name reaction which involves the conversion of phenolic esters into hydroxyaryl ketones on heating in the presence of a catalyst. Suitable catalysts for...
Keywords: Acylations, Addition reactions, Agrochemicals, Antivirals, Catalysis, Fries Rearrangement, Michael Addition, Pharmaceutical, Rearrangements, Vitamins

Peer-Reviewed Papers
15

References

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