• USA Home
  • 343935 - 4-Chlorobutyryl chloride

EMAIL THIS PAGE TO A FRIEND
343935 Aldrich

4-Chlorobutyryl chloride

technical grade, 95%

Purchase

Properties

Related Categories Acid Halides, Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks More...
grade   technical grade
vapor pressure   3 mmHg ( 20 °C)
InChI Key   CDIIZULDSLKBKV-UHFFFAOYSA-N
assay   95%
autoignition temp.   824 °F
refractive index   n20/D 1.461(lit.)
bp   173-174 °C(lit.)
density   1.26 g/mL at 25 °C(lit.)

Description

Packaging

250 mL in glass bottle

Application

4-Chlorobutyryl chloride may be used in the radiosynthesis of (11)C-levetiracetam, a potential marker for PET imaging of SV2A expression. It may be used in the preparation of N-chloroacyl-6-O-triphenylmethylchitosans.

General description

4-Chlorobutyryl chloride is a chloroacyl chloride. It undergoes coupling with 4-carboxyphenylboronic acid under standard Suzuki coupling conditions [Pd(PPh3)4, Na2CO3, DME/H2O] to give 2′-methyl-4′-(2-oxo-1-pyrrolidinyl)biphenyl-4-carboxylic acid. Synthesis of 4-chlorobutyryl chloride using γ-butyroctone has been reported.3

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3390 8(6.1) / PGI
WGK Germany 
1
RTECS 
EM1406000
Flash Point(F) 
185 °F
Flash Point(C) 
85 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?