• USA Home
  • 361798 - Lithium diisopropylamide solution

EMAIL THIS PAGE TO A FRIEND
361798 Aldrich

Lithium diisopropylamide solution

2.0 M in THF/heptane/ethylbenzene

Synonym: LDA

Purchase

Properties

Related Categories 25mL Sure/Seal Reagents, Acids & Bases, Bases, Chemical Synthesis, Organic Bases,
InChI Key   ZCSHNCUQKCANBX-UHFFFAOYSA-N
concentration   2.0 M in THF/heptane/ethylbenzene
impurities   3 wt. % diisopropylamine
density   0.812 g/mL at 25 °C
storage temp.   2-8°C

Description

Application

Titanium-ate enolates prepared from ketones by Ti(OiPr)4 and LDA underwent efficient radical trifluoromethylation providing trifluoromethyl ketones in good yield. Used in directed ortho-lithiation of arylsulfonyloxazolidinones to prepare N-substituted saccharin analogs.

Packaging

4×25, 100, 4×100, 800 mL in Sure/Seal™

The 25 mL Sure/Seal bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

Signal word 
Danger
Supplemental Hazard Statements 
May form explosive peroxides., Reacts violently with water.
RIDADR 
UN3399 - class 4.3 - PG 2 - EHS - Organometallic substance, liquid, water-reactive, flammable, HI: all (not BR)
WGK Germany 
3
Flash Point(F) 
35.6 °F
Flash Point(C) 
2 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Acids and Bases

Acids and bases have been used by chemists for centuries, and are among the most fundamental reagents employed in synthetic organic chemistry. This Aldrich product line ranges from Brønsted and Lewis...
Chemfiles Volume 1 Article 3

Related Content

Molarity Calculator and Normality Calculator for Acids and Bases

The molarity calculator tool provides lab-ready directions describing how to prepare an acid or base solution of specified Molarity (M) or Normality (N) from a concentrated acid or base solution.  To...

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?