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363057 Aldrich

6-O-Methylguanine

97%

Synonym: 2-Amino-6-methoxypurine, 6-Methoxyguanine

  • CAS Number 20535-83-5

  • Empirical Formula (Hill Notation) C6H7N5O

  • Molecular Weight 165.15

  •  Beilstein Registry Number 645384

  •  MDL number MFCD00133009

  •  PubChem Substance ID 24862349

  • Popular Documents:  FTNMR (PDF)  

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Properties

Related Categories Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, Purines
InChI Key   BXJHWYVXLGLDMZ-UHFFFAOYSA-N
assay   97%
mp   >300 °C(lit.)
Gene Information   human ... CDK2(1017), MGMT(4255)

Description

Packaging

500 mg in glass bottle

General description

6-O-Methylguanine is a purine derivative and its binding affinity has been examined by B. subtilis xpt-pbuX guanine riboswitch (GR) using isothermal titration calorimetry (ITC). 6-O-Methylguanine is formed during the alkylation of a number of purified tRNA preparations, via reaction with the carcinogens, N-methyl-N-nitrosourea .

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 363057.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Related Content

Indoles, Purines, and Their Isosteres

Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry

Peer-Reviewed Papers
15

References

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