|Related Categories||Amino Acid Derivatives, Chemical Biology, Chemical Synthesis, Peptide Chemistry, Tryptophan More...|
|optical activity||[α]20/D +18°, c = 5 in methanol|
25 g in poly bottle
5 g in glass bottle
Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry
Acyl substrate preferences of an IAA-amido synthetase account for variations in grape (Vitis vinifera L.) berry ripening caused by different auxinic compounds indicating the importance of auxin conjugation in plant development. Böttcher C, Boss PK, and Davies C J. Exp. Bot. 62(12), 4267-80, (2011)
Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase. Dunham RM, Gordon SN, Vaccari M, et al. AIDS Res. Hum. Retroviruses 29(2), 207-14, (2013)
Inhibition of Indoleamine 2,3-Dioxygenase Activity by Levo-1-Methyl Tryptophan Blocks Gamma Interferon-Induced Chlamydia trachomatis Persistence in Human Epithelial Cells. Ibana JA, Belland RJ, Zea AH, et al. Infect. Immun. 79, 4425-4437, (2011)
Human plasmacytoid dendritic cells induce CD8⁺ LAG-3⁺ Foxp3⁺ CTLA-4⁺ regulatory T cells that suppress allo-reactive memory T cells. Boor PP, Metselaar HJ, Jonge Sd, et al. Eur. J. Immunol. 41(6), 1663-74, (2011)
1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan. Yuasa HJ, Ball HJ, Austin CJ, et al. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 157(1), 10-5, (2010)
A kinetic study of the photodynamic effect on tryptophan methyl ester and tryptophan octyl ester in DOPC vesicles. Posadaz A, Correa NM, Biasutti MA, et al. Photochem. Photobiol. 86(1), 96-103, (2010)
Comment on "Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression". Sørensen RB, thor Straten P, and Andersen MH J. Immunol. 183(10), 6040, (2009)
The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels. Sun H, Greathouse DV, Andersen OS, et al. J. Biol. Chem. 283(32), 22233-43, (2008)
Can diffusion tensor imaging (DTI) identify epileptogenic tubers in tuberous sclerosis complex? Correlation with α-[11C]methyl-L-tryptophan ([11C] AMT) positron emission tomography (PET). Tiwari VN, Kumar A, Chakraborty PK, et al. J. Child Neurol. 27(5), 598-603, (2012)
Regioselective nitration of N(alpha),N(1)-bis(trifluoroacetyl)-L-tryptophan methyl ester: efficient synthesis of 2-nitro and 6-nitro-N-trifluoroacetyl-L-tryptophan methyl ester. Osborne AS, Som P, Metcalf JL, et al. Bioorg. Med. Chem. Lett. 18(21), 5750-2, (2008)
Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate. Popp FC, Eggenhofer E, Renner P, et al. Transpl. Immunol. 20(1-2), 55-60, (2008)
FT-NMR 1 (3), 152:C / RegBook 1 (2), 2417:N / Structure Index 1, 383:E:8
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?