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37640 Aldrich

2,8-Quinolinediol

≥99.0% (HPLC)

Synonym: 2,8-Dihydroxyquinoline

  • CAS Number 15450-76-7

  • Empirical Formula (Hill Notation) C9H7NO2

  • Molecular Weight 161.16

  •  Beilstein Registry Number 472906

  •  MDL number MFCD00216696

  •  PubChem Substance ID 24863440

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Properties

Related Categories Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines More...
InChI Key   ZXZKYYHTWHJHFT-UHFFFAOYSA-N
assay   ≥99.0% (HPLC)
mp   ~290 °C (dec.)

Description

Packaging

1, 5 g in glass bottle

Application

2,8-Quinolinediol is suitable for use as standard in a study to identify the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats by online and off-line LC-MS techniques. It may be used as starting reagent for the preparation of two powerful β2-adrenergic receptor agonists, used for the treatment of asthma:
• Procaterol
• Indacaterol

General description

2,8-Quinolinediol is a quinolone derivative. It has been reported as metabolite of 8-hydroxyquinoline-N-oxide in rabbits. Synthesis of 2,8-quinolinediol has been reported. It is reported as one of the six possible forms of 8-hydroxycarbostyril. It has been detected as new UV-absorbing compound (UAC) in cow milk and its structure was elucidated using HRMS and by 1H, 13C and 1H ×13C NMR.It is also known as 8-hydroxycarbostyril or 8-hydroxyquinolin-2(1H)-one.

8-hydroxyquinolin-2(1H)-one has been reported as the tautomeric form of 2,8-quinolinediol. 2,8-Quinolinediol (2,8-Dihydroxyquinoline) has been identified as one of the metabolite of quinolone formed in the culture medium of gram-negative bacteria, Pseudomonas stutzeri.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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