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37640 Aldrich

2,8-Quinolinediol

≥99.0% (HPLC)

Synonym: 2,8-Dihydroxyquinoline

  • CAS Number 15450-76-7

  • Empirical Formula (Hill Notation) C9H7NO2

  • Molecular Weight 161.16

  •  Beilstein Registry Number 472906

  •  MDL number MFCD00216696

  •  PubChem Substance ID 57649744

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Properties

Related Categories Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines More...
InChI Key   ZXZKYYHTWHJHFT-UHFFFAOYSA-N
assay   ≥99.0% (HPLC)
mp   ~290 °C (dec.)

Description

Packaging

1, 5 g in glass bottle

Application

2,8-Quinolinediol is suitable for use as standard in a study to identify the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats by online and off-line LC-MS techniques. It may be used as starting reagent for the preparation of two powerful β2-adrenergic receptor agonists, used for the treatment of asthma:
• Procaterol
• Indacaterol

General description

2,8-Quinolinediol is a quinolone derivative. It has been reported as metabolite of 8-hydroxyquinoline-N-oxide in rabbits. Synthesis of 2,8-quinolinediol has been reported. It is reported as one of the six possible forms of 8-hydroxycarbostyril. It has been detected as new UV-absorbing compound (UAC) in cow milk and its structure was elucidated using HRMS and by 1H, 13C and 1H ×13C NMR.It is also known as 8-hydroxycarbostyril or 8-hydroxyquinolin-2(1H)-one.

8-hydroxyquinolin-2(1H)-one has been reported as the tautomeric form of 2,8-quinolinediol. 2,8-Quinolinediol (2,8-Dihydroxyquinoline) has been identified as one of the metabolite of quinolone formed in the culture medium of gram-negative bacteria, Pseudomonas stutzeri.

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Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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