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379395 Aldrich

Ethyl 1-piperidineacetate

98%

Synonym: Piperidin-1-ylacetic acid ethyl ester

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Properties

Related Categories Building Blocks, C9, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
InChI Key   LXZHLNWWDDNIOJ-UHFFFAOYSA-N
assay   98%
refractive index   n20/D 1.453(lit.)
bp   109-111 °C/25 mmHg(lit.)
density   0.984 g/mL at 25 °C(lit.)

Description

Packaging

5 mL in glass bottle

Application

Reactant for synthesis of:
Nicotinic acid receptor agonists for treatment of dyslipidemia
1-Alkylcyclanols with side chain functions
Benzhydrylamides for pharmacochemical studies

Reactant for:
Elimination reactions
Hydrogenation of esters to alcohols

General description

Ethyl 1-piperidineacetate (Piperidin-1-ylacetic acid ethyl ester) is an α-amino acid ethyl ester derivative. Thermal decomposition of ethyl 1-piperidineacetate in gas phase has been studied by ab initio theoretical methods. The kinetics of gas-phase decomposition of ethyl 1-piperidineacetate to the corresponding α-amino acid derivative and ethylene over the temperature range of 360-430°C and pressure range of 26-86Torr has been investigated. Alkylation reaction of ethyl 1-piperidineacetate with ethyl bromoacetate in absolute ethanol has been reported to obey second order kinetics.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
WGK Germany 
3
Flash Point(F) 
195.8 °F
Flash Point(C) 
91 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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