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379492 Aldrich

1-Acetylindoline

98%

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Properties

Related Categories Building Blocks, C10, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
InChI Key   RNTCWULFNYNFGI-UHFFFAOYSA-N
assay   98%
mp   102-104 °C(lit.)

Description

Packaging

5 g in glass bottle

Application

• Reactant for preparation of triazolothiadiazepine dioxide derivatives
• Reactant for preparation of halo-substituted aromatic amides
• Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists
• Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents
• Reactant for regioselective ortho Suzuki-Miyaura coupling reaction

1-Acetylindoline may be used in the synthesis of 5-chloroindole.

General description

1-Acetylindoline, a substituted indole, is a tertiary amide having bulky N-groups. Its reduction to the corresponding amine, by reaction with silane in the presence of MoO2Cl2 (catalyst), has been reported.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
NM1892500
Protocols & Articles
Peer-Reviewed Papers
15

References

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