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389145 Aldrich

(2-Hydroxypropyl)-β-cyclodextrin

average Mw ~1,540

DOWNLOAD MSDS (PDF)

Synonym: (2-Hydroxypropyl)-beta-cyclodextrin

(2-Hydroxypropyl)-β-cyclodextrin average Mw ~1,540
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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Capillary Electrophoresis, Chelation/Complexation Compounds, Chemical Synthesis,
optical activity   [α]23/D +125°, c = 1 in H2O
mol wt   average Mw ~1,540
extent of labeling   1.0 molar substitution dextrin

Description

Application

The solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice.

Packaging

25 g in poly bottle

5 g in glass bottle

Price and Availability

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