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391204 Aldrich

Methyl pipecolinate hydrochloride

97%

Synonym: Methyl 2-piperidinecarboxylate hydrochloride

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Properties

Related Categories Building Blocks, C5 to C7, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
InChI Key   APCHKWZTSCBBJX-UHFFFAOYSA-N
assay   97%
mp   205 °C (dec.)(lit.)

Description

Packaging

5, 25 g in glass bottle

Application

Reactant for synthesis of:
A pipecolic linker
Antiviral agents
Aurora and epidermal growth factor receptor kinase inhibitor
Pyrrolidine derivatives via reduction of substituted pyrroles

Reactant for:
Petasis reactions
Decarbonylative radical cyclization of alpha-amino selenoesters upon electrophilic alkenes

General description

Methyl pipecolinate hydrochloride is a hydrochloride salt of methyl piperidine-2-carboxylate (methyl pipecolinate). The kinetics of the enzymatic separation of enantiomeric forms of methyl pipecolinate using Candida antarctica Lipase A (CAL-A) has been reported. Its role as catalyst for the standard Diels-Alder reaction has been examined.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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