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391468 Aldrich

4-Hydroxypiperidine hydrochloride

98%

Synonym: 4-Piperidinol hydrochloride

  • CAS Number 5382-17-2

  • Empirical Formula (Hill Notation) C5H11NO · HCl

  • Molecular Weight 137.61

  •  Beilstein Registry Number 3908995

  •  EC Number 226-374-7

  •  MDL number MFCD00035298

  •  PubChem Substance ID 24864381

  • Popular Documents:  FTIR (PDF)  

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Properties

Related Categories Building Blocks, C5 to C7, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
InChI Key   VKCORPXOKYDINR-UHFFFAOYSA-N
assay   98%
mp   155-157 °C(lit.)
solubility   methanol: soluble25 mg/mL, clear, colorless

Description

Packaging

5 g in glass bottle

Application

4-Hydroxypiperidine hydrochloride is suitable for use in the Ugi-multi component reaction (MCR) to study the use of miniaturised-synthesis and Total Analysis System (mSYNTAS) in solution phase synthesis and on-line analysis of Ugi-MCRs. It may be used in the synthesis of acetic acid-piperidine-4-yl ester.

Reactant for synthesis of:
14C-labeled E4010
PET tracer for imaging brain acetylcholinesterase

Reactant for allosteric modulators of metabotropic glutamate receptor subtype 5

General description

4-Hydroxypiperidine hydrochloride is a piperidine derivative. The synthesis of 4-hydroxypiperidine has been reported. 4-Hydroxypiperidine participates in the synthesis of 4-(4′-hydroxypiperidino)-4-phenylcyclohexanol and 1-(4-hydroxypiperidino)cyclohexanecarbonitrile. 4-Hydroxypiperidine is the starting material for the synthesis of Sibrafiban and Lamifiban, two non-peptidefibrinogen receptor.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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