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393851 Aldrich

2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde

97%

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Properties

Related Categories Aldehydes, Building Blocks, C9, Carbonyl Compounds, Chemical Synthesis,
InChI Key   ZBOUXALQDLLARY-UHFFFAOYSA-N
assay   97%
mp   128-130 °C(lit.)

Description

Packaging

1 g in glass bottle

Application

2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde (2-hydroxy-5-methylisophthalaldehyde) is suitable reagent used in the synthesis of 2-(2′-vinyloxyethoxy)-5-methylisophthaldehyde and chiral calixsalen macrocycles.
2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde may be used in the synthesis of the following:
• 3-[(2,4-Dichlorophenyl)iminomethyl]-2-hydroxy-5-methylbenzaldehyde, a Schiff base.
• 2-Hydroxy-3-methoxymethyl-5-methylbenzaldehyde.
• Acyclic Schiff-base ligands.
• Macrobicyclic ligands (MSB).
• 4-Methyl-2,6-divinylphenol.
• 2-Hydroxy-3-dimethoxymethyl-5-methylbenzaldehyde.

General description

2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde (2-hydroxy-5-methylisophthalaldehyde) is a dialdehyde derivative. It has been synthesized by heating p-cresol with hexamethylenetetramine. The structure has been confirmed by 1H and 13C NMR. It is an important raw material for the synthesis of various binucleating schiff base ligand.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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