• USA Home
  • 394815 - N-Maleoyl-β-alanine

EMAIL THIS PAGE TO A FRIEND
394815 Aldrich

N-Maleoyl-β-alanine Green Alternative

97%

Synonym: 3-Maleimidopropionic acid, N-(2-Carboxyethyl)maleimide

  • CAS Number 7423-55-4

  • Empirical Formula (Hill Notation) C7H7NO4

  • Molecular Weight 169.13

  •  Beilstein Registry Number 1528952

  •  MDL number MFCD00043030

  •  PubChem Substance ID 24864618

  • Popular Documents:  FTIR (PDF)  

Purchase

Properties

Related Categories Building Blocks, Carbonyl Compounds, Chemical Synthesis, Cyclic Imides, Greener Alternative Products,
InChI Key   IUTPJBLLJJNPAJ-UHFFFAOYSA-N
assay   97%
greener alternative product score   old score: 17
new score: 6
Find out more about DOZN™ Scoring.
greener alternative product characteristics   Atom Economy
Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
mp   103-106 °C(lit.)
greener alternative category   Re-engineered
storage temp.   2-8°C

Description

Packaging

1 g in glass bottle

250 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

N-Maleoyl-β-alanine (3-maleimidopropanoic acid, N-(2-carboxyethyl)maleimide)) is the suitable reagent used in the following studies:
• To decrease the biotin binding affinity of Avd(S16C) (avidin with a single point mutation S16C).
• As a side chain reactive agent to modify tryptic peptides that result in mass shifts indicating the presence of cysteine residues.
• To preblock Xenopus laevis oocytes for exposed cysteines used as an expression system in the study of conformational changes in cASIC1a Receptors.
It may be used in the following studies:
• As a protective agent for keratin fiber in high temperature process.
• As a non-cleavable maleimido moiety during the synthesis of tetrawalled molecular umbrella-octaarginine conjugates.
• Synthesis of organotin carboxylates of N-Maleoyl-β-alanine.
• To functionalize the gold surfaces to interact with cysteine-modified peptide.
• Preparation of cross-linked dextran–poly(ethylene glycol) hydrogel substrate.

General description

N-Maleoyl-β-alanine (3-maleimidopropanoic acid) is an aliphatic N-substituted maleimide. It is one of the component of the stabilizing solution for EC145 (a folate-targeted vinca alkaloid conjugate) used in rodent pharmacokinetic studies.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?