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396788 Aldrich

Ethyl formimidate hydrochloride

Synonym: Ethyl methanimidate hydrochloride

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Properties

Related Categories Amidates/Imidates, Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks More...
InChI Key   JPUTTYRVDANTBN-UHFFFAOYSA-N
mp   75 °C (dec.)(lit.)
storage temp.   2-8°C

Description

Packaging

10 g in glass bottle

Application

Ethyl formimidate hydrochloride may be used in the preparation of the following:
• 5-aminoimidazole-4-carboxylic acid α- and β-ribotides
• s-triazines
• 2,3:5,6-di-O-isopropylidene-α- and -β-5-amino-4-ethoxycarbonyl or -carbamoyl-imidazole D-mannofuranosides
• 5-amino-1-(2-pyridyl)imidazole

Reactant involved in the synthesis of biologically active molecules including:
• Bredinin via amination of an acyclic precursor
• Amidine conjugates of the ornithine moiety of an antifungal

Reactant involved in:
• Intermolecular cyclization
• Mo-catalyzed asymmetric ring-closing metathesis for synthesis of cyclid amides and amines
• Synthesis of peptidic 1-cyanopyrrolidines

General description

Ethyl formimidate hydrochloride is a nitrogen containing organic building block. On heating it undergoes degradation to afford formamidine hydrochloride, ethyl formate and ethyl chloride.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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