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415294 Aldrich

5-Iodo-1,3-dimethyluracil

99%

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Properties

Related Categories Building Blocks, C6 to C8, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks,
InChI Key   XUUVRIXNFFFPCM-UHFFFAOYSA-N
assay   99%
mp   225 °C (dec.)(lit.)
solubility   DMSO: soluble10 mg/mL(lit.)

Description

Packaging

1 g in glass bottle

Application

5-Iodo-1,3-dimethyluracil may be used for the synthesis of N-[2-[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)thio]-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)yl]methanesulfonamide.

General description

The effect of 5-iodo-1,3-dimethyluracil on the incorporation of [125I] 5-iodo-2′-deoxyuridine [125I radiolabelled IdUrd] in DNA of cancer cells has been studied. Synthesis of 5-iodo-1,3-dimethyluracil from aromatic organomercurials; 5-(acetoxymercurio)-1,3-dimethyluracil or 5,5′-mercuriobis(1,3-dimethyluracil) has been reported.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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