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420107 Aldrich

Bromotris(dimethylamino)phosphonium hexafluorophosphate

98%

Synonym: BroP, Bromotris(N-methylmethanaminato)-phosphorus hexafluorophosphate

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling,
InChI Key   XELPBWPBGHCIKX-UHFFFAOYSA-N
assay   98%
mp   >300 °C(lit.)

Description

Packaging

250 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Reagent for:
Conjugate addition of nitroalkanes to an acrylate equivalent
A novel polymer supported approach to nucleoside modification
Asymmetric hydrogenations
Peptide coupling
Pyrrolidine hydroxylation
Synthesis of cyclic PNA-based compound directed against HIV-1 TAR RNA

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3263 8 / PGII
WGK Germany 
3
Protocols & Articles

Articles

Phosphonium Salts

Phosphonium salts are powerful and easy-to-use peptide coupling reagents that allow in situ generation of active esters. After the recognition of chlorotris(dimethylamino)phosphonium as the activatin...
Matthias Junkers
Aldrich ChemFiles 2007, 7.2, 8.
Keywords: Chemfiles, Peptide synthesis

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COMU – Safer and More Efficient Peptide Coupling Reagent

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