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420107 Aldrich

Bromotris(dimethylamino)phosphonium hexafluorophosphate

98%

Synonym: BroP, Bromotris(N-methylmethanaminato)-phosphorus hexafluorophosphate

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling,
InChI Key   XELPBWPBGHCIKX-UHFFFAOYSA-N
assay   98%
mp   >300 °C(lit.)

Description

Packaging

250 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Reagent for:
Conjugate addition of nitroalkanes to an acrylate equivalent
A novel polymer supported approach to nucleoside modification
Asymmetric hydrogenations
Peptide coupling
Pyrrolidine hydroxylation
Synthesis of cyclic PNA-based compound directed against HIV-1 TAR RNA

Price and Availability


Laboratory Gloves

Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3263 8 / PGII
WGK Germany 
3
Protocols & Articles

Articles

Phosphonium Salts

Phosphonium salts are powerful and easy-to-use peptide coupling reagents that allow in situ generation of active esters. After the recognition of chlorotris(dimethylamino)phosphonium as the activatin...
Matthias Junkers
Aldrich ChemFiles 2007, 7.2, 8.
Keywords: Chemfiles, Peptide synthesis

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COMU – Safer and More Efficient Peptide Coupling Reagent

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