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422460 Aldrich

2-Thiazolecarboxaldehyde

97%

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Properties

Related Categories Aldehydes, Building Blocks, C1 to C6, C3 to C7, Carbonyl Compounds,
InChI Key   ZGTFNNUASMWGTM-UHFFFAOYSA-N
assay   97%
refractive index   n20/D 1.574(lit.)
bp   61-63 °C/15 mmHg(lit.)
density   1.288 g/mL at 25 °C(lit.)
storage temp.   2-8°C

Description

Packaging

1 g in glass bottle

Application

2-Thiazolecarboxaldehyde may be used as a reactant in the following syntheses:
• Benzothiazine N-acylhydrazones, having potential antinociceptive and anti-inflammatory activity.
• Thiazole-2-yl-(amino)methylphosphonate diethyl esters.
• Imino ester by reacting with L-leucine t-butyl ester hydrochloride.

Useful building block for taxane analogs.

General description

2-Thiazolecarboxaldehyde is a thiazole aldehyde derivative. It undergoes Baylis–Hillman reaction with methyl acrylate catalyzed by DABCO (1,4-diazabicyclo[2.2.2]octane). The reaction mechanism has been studied by electrospray ionization mass spectrometry (ESI-MS).

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Safety & Documentation

Safety Information

WGK Germany 
3
Flash Point(F) 
154.4 °F
Flash Point(C) 
68 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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