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42358 Aldrich

Dioctadecylamine

≥99.0% (NT)

Synonym: DODA, Distearylamine

  • CAS Number 112-99-2

  • Linear Formula [CH3(CH2)17]2NH

  • Molecular Weight 521.99

  •  Beilstein Registry Number 1801688

  •  EC Number 204-020-2

  •  MDL number MFCD00048494

  •  PubChem Substance ID 24866510

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Properties

Related Categories Amines, Building Blocks, C20 to C30+, Chemical Synthesis, Nitrogen Compounds,
InChI Key   HKUFIYBZNQSHQS-UHFFFAOYSA-N
assay   ≥99.0% (NT)
mp   71-73 °C
solubility   water: soluble(lit.)

Description

Packaging

5 g in glass bottle

Application

Dioctadecylamine (DODA) is suitable reagent used in the synthesis of the following:
• Dioctadecylamine-BCN (bicyclo[6.1.0]nonyne) conjugate.
• Lipid derivatives of bisethylnorspermine (BSP).
• Functional VP (N-vinylpyrrolidone ) polymers.
It may be used in the following studies:
• As a reactant in the synthesis of 4,4’-azobis(4-cyano-N,N-dioctadecyl)pentanamide (DODA-501) by reacting with disuccinimidyl 4,4’-azobis(4-cyanovalerate).
• As a reagent in the synthesis of dioctadecyl heptapeptides.
• As a phase transfer and stabilizer agent for gold nanoparticles (AuNPs) in non-polar solvent.

General description

Dioctadecylamine (DODA), a secondary amine, is a fatty amine derivative. Its biodegradation potential has been assessed. It has been observed that in aqueous medium DODA self organizes into plate like structures. Its partial charge distribution as a function of its conformation has been analyzed. The phase diagram of dioctadecylamine Langmuir monolayers has been determined and investigations show it does not form a monolayer above pH 3.9. DODA has been utilized in forming liposomes, cationic lipids or lipid chelating agents.

Price and Availability

Suggested Laboratory Gloves


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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