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424048 Aldrich

2,6-Quinolinediol

Synonym: 2,6-Dihydroxyquinoline, 6-Hydroxycarbostyril

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Properties

Related Categories Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines More...
InChI Key   AQLYZDRHNHZHIS-UHFFFAOYSA-N
mp   >300 °C(lit.)

Description

Packaging

1 g in glass bottle

250 mg in glass insert

Application

2,6-Quinolinediol may be used as a test compound to investigate the carcinogenicity of the naturally occurring quinoline metabolite of tryptophan. The study was conducted by suspending tryptophan metabolites in cholesterol pellets, followed by the surgical implantation of the pellets into the mice bladder. It may be used as a reactant in the synthesis of 2-chloro-6-quinolinol by reacting with POCl3 (phosphorus oxychloride).

Reactant involved in synthesis of:
• (Benzyloxy)methylquinolinone derivatives for use as PDE3 inhibitors
• Substances related to cilostazol
• 2,6-Quinolinyl derivatives for use as VLA-4 / VCAM-1 antagonists

General description

2,6-Quinolinediol is a substituted quinoline compound. It has been prepared starting from 6-methoxyquinoline. It has been reported to be one of the UV-absorbing compounds (UAC) found in cow milk.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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