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432725 Aldrich

2,4-Dimethoxybenzylamine

98%

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Properties

Related Categories Amines, Building Blocks, C9, Chemical Synthesis, Nitrogen Compounds,
InChI Key   QOWBXWFYRXSBAS-UHFFFAOYSA-N
assay   98%
refractive index   n20/D 1.549(lit.)
bp   140 °C/1 mmHg(lit.)
density   1.113 g/mL at 25 °C(lit.)

Description

Packaging

5, 25 mL in glass bottle

Application

2,4-Dimethoxybenzylamine is an amine nucleophile used to investigate the 1,4- reactivity of 5-bromo-2-indene-1-one. It may be used in the following studies:
• As an ammonia equivalent in the concise synthesis of a series of 2,4,5-trisubstituted oxazoles, via a tandem Ugi/Robinson-Gabriel reaction sequence.
• Total synthesis of (-)-muraymycin (MRY) D2 and its epimer, the antibacterial nucleoside natural product.
• Two-step synthesis of amide derivatives of uracil polyoxin C (UPOC) methyl ester using the Ugi reaction.
• Synthesis of N-hydroxythiourea.
• Synthesis of anti-HIV-1 agents.

General description

2,4-Dimethoxybenzylamine can be preprepared by reduction (NaBH4 , BF3.OEt2, THF) of 2,4-dimethoxybenzonitrile.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2735PSN1 8 / PGIII
WGK Germany 
3
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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