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437352 Aldrich

4-(1-Pyrrolidinyl)piperidine

95%

Synonym: 1-(Piperidin-4-yl)pyrrolidine

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Properties

Related Categories Building Blocks, C9, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
InChI Key   STWODXDTKGTVCJ-UHFFFAOYSA-N
assay   95%
mp   53-56 °C(lit.)

Description

Packaging

1, 5 g in glass bottle

Application

4-(1-Pyrrolidinyl)piperidine was employed for the synthesis of the following analogs:
• 4-pyrrolidin-1´-yl-1-[2-(2″-nitro-phenyl)-2-oxo-ethyl]-piperidinium bromide
• 4-pyrrolidin-1´-yl-1-[2-(3″-nitro-phenyl)-2-oxo-ethyl]-piperidinium bromide
• 4-pyrrolidin-1´-yl-1-[2-(2″,4″-dimethoxy-phenyl)-2-oxo-ethyl]-piperidinium bromide
• 4-pyrrolidin-1´-yl-1-[2-(3″,4″-dihydroxy-phenyl)-2-oxo-ethyl]-piperidinium bromide

Reactant for synthesis of:
Small molecule ligands of methyl-lysine binding proteins
Small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells
Selective Polo-like kinase 1 inhibitors
Molecules with effects on plasma glucose levels
Vasopressin1b receptor antagonists
IKKβ inhibitors

General description

4-(1-Pyrrolidinyl)piperidine (4-pypp) has been reported to form Hofmann type complexes [M(4-pypp)2Ni(CN)4] (M=Ni or Co) and their FT-IR and Raman spectra have been studied. FT-IR, Raman spectra and the vibrational spectra of 4-pypp have been recorded between 4000 and 400cm-1.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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