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448877 Aldrich

Chitosan

medium molecular weight

Synonym: Deacetylated chitin, Poly(D-glucosamine)

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Properties

Related Categories 3D Printing Materials for Research and Development, Chitosan, Chitosan and Chitin, Chitosans (Animal Origin), Materials Science,
viscosity   200-800 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)
solubility   dilute aqueous acid: soluble

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Packaging

50, 250 g in poly bottle

Physical form

75-85% deacetylated

Application

Flocculant, protein precipitation, encapsulating agent and aqueous thickener.

Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Price and Availability


3D Printing

The Future of Bioimaging
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
nwg

Documents

Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
What is the molecular weight range for Product 448877, Chitosan?
The molecular weight is 190,000-310,000 based on viscosity
What is the solubility of Product 448877, Chitosan? 
Chitosan is insoluble in water or organic solvents.  Hazy solutions can be prepared in 1 M acetic acid (10 mg/ml), but extensive sonication may be required to fully suspend and dissolve the material.  It is also soluble in dilute acidic aqueous solvents.
What are the molecular weights of the chitosan products you offer, Products 448869, 448877, and 419419?
We offer three different sizes of chitosan.  Our low molecular weight chitosan (Product 448869) is 50,000-190,000 Da.  Our medium molecular weight chitosan (Product 448877) is 190,000-310,000 Da.  Our high molecular weight chitosan (Product 419419) is ~310,000 TO >375,000 Da.
What are some uses for chitosan?
Chitosan is a biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery. Please note that Product No. 419419 is for research purposes only, not for cosmetic or drug use.
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
Show more questions
Protocols & Articles

Articles

3D Printing of Carbon Fiber-Reinforced Composites

3D printing is a type of additive manufacturing that can be used to rapidly fabricate components with highly customizable geometries, most typically using a layer-by-layer fabrication process. 3D pri...
Zhenyu Bo* (Ph.D Candidate at Northwestern University) and Jia Choi*, PhD, Product Manager


*Materials Science Product Management Team, MilliporeSigma, Milwaukee, WI.
Keywords: Deposition, Nanomaterials, Nanotubes

Chitosan Biopolymer from Fungal Fermentation for Delivery of Chemotherapeutic Agents

David Brown,1 Keith Brunt,2 Nils Rehmann3 1CTO Mycodev Group, Fredericton, NB E3B 6B3 Canada 2Dalhousie School of Medicine New Brunswick, Saint John, NB E2K 5E2, Canada 3NiRem Consulting, 8 Fish Hatc...
David Brown, Keith Brunt, Nils Rehmann
Material Matters, 2016, 11.3
Keywords: Antimicrobials, Bacterial conjugations, Cancer, Click chemistry, Clinical, Fermentation, Hemostatics, Pharmaceutical, Titrations

Chitosan-based Biomaterials

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose. It is the primary, high modulus fibrous component of the exoskeleton of arthropods incl...
Guolin Wu1, Hui Gao2, and Jianbiao Ma1,2
Material Matters, 2012 v7, n3
Keywords: Absorption, Applications, Cell attachment, Cell culture, Degradations, Dialysis, Diseases, Growth factors, Metabolites, Methods, Pharmaceutical, Purification, Renal Disease, Transfection, Vectors

Chitosan: A Versatile Platform for Pharmaceutical Applications

Raphael Riva and Christine Jerome* Center for Education and Research on Macromolecules University of Liege, Chemistry Department, Sart-Tilman, Building B6a, 4000 Liege, Belgium *Email: c.jerome@ulg.a...
Keywords: Acetylations, Adhesion, Aminations, Cancer, Condensations, Coupling reactions, Degradations, Derivatizations, Ethoxylations, Growth factors, Ligands, Pharmaceutical, Polymerization reactions, Precipitation, Reductions, Reductive aminations, Solvents, Substitutions, Transfection

Injectable Hydrogels for Cell Delivery and Tissue Regeneration

Prathamesh M. Kharkar,1 April M. Kloxin1,2* 1Materials Science and Engineering and 2Chemical and Biomolecular Engineering University of Delaware, Newark, DE 19716 USA *Email: akloxin@udel.edu
Keywords: Addition reactions, Adhesion, Angiogenesis, Biochemistry, Biomaterials, Building blocks, Cardiovascular, Catalysis, Cell proliferation, Click chemistry, Clinical, Cycloadditions, Degradations, Growth factors, Reversed-phase chromatography

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Jiayu Leong,1 Liam Grover,2 Hyunjoon Kong1* 1Department of Chemical and Biomolecular Engineering University of Illinois, Urbana-Champaign, IL 61801 USA 2University of Birmingham, UK *Email: hjkong06@...
Keywords: Adhesion, Adsorption, Aminations, Bacterial conjugations, Biomaterials, Building blocks, Cell culture, Clinical, Deaminations, Degradations, Deposition, Diffusion, Growth factors, Hydroxylations, Immobilization, Ligands, Methylations, Michael reaction, PAGE, Purification, Recombination, Reductive aminations, Transfection

Three-Dimensional Printing of Tissue Engineering Scaffolds

Helena N. Chia, Ph.D.,1* Benjamin M. Wu, D.D.S, Ph.D.1,2* 1Department of Bioengineering, Henry Samueli School of Engineering University of California, Los Angeles, CA 90095 USA 2Division of Advanced ...
Keywords: Biomaterials, Ceramics, Chromatin immunoprecipitation, Deposition, Diagnostic Imaging, Diffusion, Growth factors, Materials Science, Melting, Polymerization reactions, Solvents

Related Content

Chitosan Microparticles

Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals. The objective of this study was to assess the effect of processin...
Keywords: Acetylations, Microscopy, Scanning electron microscopy

Peer-Reviewed Papers
15

References

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