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473049 Aldrich

(1S,4S)-(−)-2-Boc-2,5-diazabicyclo[2.2.1]heptane

95%

Synonym: tert-Butyl (1S,4S)-(−)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

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Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Other Heterocyclic Building Blocks More...
InChI Key   UXAWXZDXVOYLII-YUMQZZPRSA-N
assay   95%
optical activity   [α]22/D −44°, c = 1 in chloroform
mp   74-76 °C(lit.)

Description

Packaging

1, 5 g in glass bottle

250 mg in glass bottle

Application

(1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane may be used in the preparation of 2-boc-5-(4-nitrophenyl)-2,5-diaza-bicyclo[2.2.1]heptane by reacting with p-nitrobenzene.
It may also be used to develop:
• indazolylpyrazolo[1,5-a]pyrimidine analogs based B-Raf inhibitors
• CCR2 antagonists
• α4β2 nicotinic acetylcholine receptor (nAChR) partial agonists
• azabicyclic sulfonamide based 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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