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475696 Aldrich

Poly(ethylene glycol) diglycidyl ether

average Mn 500

Synonym: Diepoxy PEG, PEG diglycidyl ether, Polyoxyethylene bis(glycidyl ether)

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Properties

Related Categories Epoxide, Homobifunctional PEGs, Materials Science, Poly(ethylene glycol) and Poly(ethylene oxide), Polymer Science,
mol wt   average Mn 500
refractive index   n20/D 1.47
density   1.14 g/mL at 25 °C(lit.)
Ω-end   Glycidyl
α-end   Glycidyl
Polymer architecture   linear, homobifunctional
cross-linking reagent for   amine reactive
storage temp.   2-8°C

Description

Packaging

100, 500 mL in poly bottle

Application

The high solubility of PEGDGE has been successfully employed to immobilize glucose oxidase, d-amino acid oxidase and glutamate oxidase. It may be used as a component for the development of microelectrode biosensors to detect hydrogen peroxide and nitric oxide.

General description

Poly(ethylene glycol) diglycidyl ether (PEGDGE) shows highly solubility in water. Hence, it easily undergoes hydrolysis followed by ring cleavage reaction in aqueous solution, yielding hydroxyl group. PEGDGE combines with proteins covalently or non-covalently. PEGDGE is widely used in chemical industries for cross linking and surface modifier.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
386.6 °F
Flash Point(C) 
197 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. For decades, research in polymeric biomateria...
Keywords: Absorption, Angiogenesis, Biomaterials, Catalysis, Cell culture, Degradations, Eliminations, Growth factors, Infrared spectroscopy, Ligands, Michael Addition, Polymerization reactions, Ring-opening polymerization

Patterning of PEG-based Hydrogels - Engineering Spatial Complexity

Most biomaterial scaffolds developed for tissue engineering applications are relatively homogeneous and lack the complexity and organization of the in vivo cellular microenvironment. While these homo...
Mariah S. Hahn
Material Matters 2010, 5.3, 62.
Keywords: Absorption, Adhesion, Adsorption, Applications, Bacterial conjugations, Biomaterials, Confocal microscopy, Diffusion, Immobilization, Methods, Polymerization reactions, Radical polymerization

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a three-dimensional (3D) fashion is a challenging requireme...
1,2Malar A. Azagarsamy, 1Navakanth R. Gandavarapu, 1,2Kristi S. Anseth*
Material Matters, 2012 v7, n3
Keywords: Addition reactions, Adhesion, Applications, Biomaterials, Catalysis, Cell culture, Cell signaling, Chemical reactions, Click chemistry, Cycloadditions, Degradations, Growth factors, Huisgen Cycloaddition, Ligands, Methods, Michael Addition, Peptide synthesis, Polymerization reactions, Step-growth polymerization, Tools, Type

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

1,2Malar A. Azagarsamy, 1Navakanth R. Gandavarapu, 1,2Kristi S. Anseth* 1Department of Chemical and Biological Engineering and 2the Howard Hughes Medical Institute, University of Colorado at Boulder,...
Keywords: Addition reactions, Adhesion, Biomaterials, Catalysis, Cell culture, Cell signaling, Chemical reactions, Click chemistry, Cycloadditions, Degradations, Growth factors, Huisgen Cycloaddition, Ligands, Michael Addition, Peptide synthesis, Polymerization reactions, Step-growth polymerization

Peer-Reviewed Papers
15

References

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