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511188 Aldrich

Methyl indole-5-carboxylate

99%

Synonym: Indole-5-carboxylic acid, methyl ester

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Properties

Related Categories Building Blocks, C10, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
InChI Key   DRYBMFJLYYEOBZ-UHFFFAOYSA-N
assay   99%
mp   126-128 °C(lit.)

Description

Packaging

1, 5 g in glass bottle

Application

Methyl indole-5-carboxylate may be used as a reactant in the following processes:
• biosynthesis of inhibitors of protein kinases
• metal-free Friedel-Crafts alkylation
• preparation of diphenylsulfonium ylides from Martin′s sulfurane
• cross dehydrogenative coupling reactions
• synthesis of indirubin derivatives
• preparation of aminoindolylacetates

Methyl indole-5-carboxylate may be used in the preparation of:
• methyl indoline-5-carboxylate
• 1H-indole-5-carbohydrazide
• dimethyl 1H-indole-3,5-dicarboxylate

General description

Methyl indole-5-carboxylate (Methyl 1H-indole-5-carboxylate), a substituted 1H-indole, can be prepared by the esterification of indole-5-carboxylic acid. Its efficacy as a substrate for indigoid generation has been assessed.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Indoles

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Peer-Reviewed Papers
15

References

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