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511412 Aldrich

Ethyl 2-methylindole-3-carboxylate

99%

Synonym: 2-Methylindole-3-carboxylic acid ethyl ester

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Properties

Related Categories Building Blocks, C12, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
InChI Key   ICXKIKDXKRONLF-UHFFFAOYSA-N
assay   99%
mp   134-136 °C(lit.)

Description

Packaging

1 g in glass bottle

Application

Reactant for preparation of:
• 2-methyl-3-[5-substituted phenyl-1,3,4-oxadiazol-2-yl]-1H-indoles as antimicrobial agents
• Aminoheterocycle via N-amination of heterocyclic compounds with O-benzoylhydroxylamines

General description

Ethyl 2-methylindole-3-carboxylate is a 2-substituted 1H-indole-3-carboxylate derivative. It can be prepared by reacting 2-iodoaniline with ethyl acetoacetate sodium salt in the presence of copper iodide.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Indoles

Sigma-Aldrich is proud to offer a new series of ChemFiles—called Privileged Structures, to our Drug Discovery and Organic Synthesis customers. Each piece will highlight a specific motif, selected app...
Chemfiles Volume 4 Article 8
Keywords: Applications, Building blocks, Cardiovascular, Chemfiles, Company, Diabetes, Diseases, Drug discovery, Medicinal chemistry, Organic synthesis, Respiratory

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