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512834 Aldrich

3-(Hydroxymethyl)phenylboronic acid

Synonym: 3-Hydroxymethylbenzeneboronic acid

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Properties

Related Categories Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Monosubstituted Aryl Boronic Acids,
InChI Key   HGTDLKXUWVKLQX-UHFFFAOYSA-N
mp   95-99 °C(lit.)

Description

Other Notes

Contains varying amounts of anhydride

Packaging

1, 10 g in glass bottle

Application

Reactant involved in:
• Copper-mediated trifluoromethylation
• Copper-catalyzed transformations from arylboronic acids in water
• Mitsunobu, Suzuki, and amidation reactions with hydroxyphenylamino bromopyrazinecarboxylate

Reactant involved in the synthesis of biologically active molecules including:
• Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors via Suzuki coupling reactions
• HIV protease inhibitors with antiviral activity against drug-resistant viruses
• Pyrrole derivatives for use as PDE4B inhibitors

Price and Availability


KitAlysis - Increasing Catalysis Productivity

Cross-Coupling Guide
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Arylboronic Acids

Aldrich is pleased to present its complete selection of arylboronic acids, the building blocks of the Suzuki coupling experiment. Most arylboronic acids readily undergo dehydration reactions to give ...
Aldrich ChemFiles 2001, 1.1, 5.
Keywords: Building blocks, Coupling reactions, Dehydration reaction, Suzuki coupling

Boronic Acids - Aldrich ChemFiles 2007, 7.7, 3.

Most boronic acids readily undergo dehydration reactions to give a cyclic (trimer) anhydride. Our selection of boronic acids may contain varying amounts of this cyclic anhydride. Fortunately, the aci...
Aldrich ChemFiles 2007, 7.7, 3.
Keywords: Chemfiles, Coupling reactions, Dehydration reaction, Suzuki coupling

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