|Related Categories||Chemical Biology, Chemical Synthesis, Coupling, Fluorination, Fluorination Reagents,|
1, 5 g in glass bottle
Reagent for synthesis of:
Cationic antimicrobial β-2,2-amino acid derivatives1
Philanthotoxin analogues for inhibition of the ionotropic glutamate receptor2
Small β-peptidomimetics for antimicrobials3
Amine prodrugs of selective neuronal nitric oxide synthase inhibitors4
Selective cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors5
Hydrazone ligation to assemble multifunctional viral nanoparticles6
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Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26-36|
Phosgene is an extremely versatile reagent allowing easy access to isocyanates, ureas, carbamates, carbonates, acyl and alkyl chlorides.1 Many of these can be used as reactive intermediates in peptid...
Aldrich ChemFiles 2007, 7.2, 4.
Keywords: Coupling reactions, Peptide synthesis
Peptide synthesis relies heavily on efficient and reliable coupling reagents. A low tendency for racemization is a key requirement. This is especially true for solid phase peptide synthesis—quantitat...
Keywords: Building blocks, Calorimetry, Condensations, Coupling reactions, Epimerizations, PEGylations, Peptide synthesis, Racemizations, Solid phase peptide synthesis, Solvents
2. Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: discovery of nanomolar, nonselective, and use-dependent antagonists. S. Froelund, et al., J. Med. Chem. 53, 7441-7451, (2010)
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