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529249 Aldrich

2-Chloro-1,3-dimethylimidazolinium chloride

Synonym: 2-Chloro-4,5-dihydro-1,3-dimethyl-1H-imidazolium chloride, DMC

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling,
InChI Key   AEBBXVHGVADBHA-UHFFFAOYSA-M
mp   133-140 °C(lit.)

Description

Application

Activating agent in total synthesis of macroviracin A, cycloviracin B1, and cyclic silanes.

Reagent for synthesis of:
Tagged glucose as an intermediate in the synthesis of branched oligosaccharides
Fluorescent chemosensors
1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1
Allosteric glucokinase activators

Reactant for synthesis of:
Organic azides from primary amines

Reagent for aza-Henry reactions

Packaging

5, 25, 100 g in glass bottle

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Imidazolium Derived Reagents

N-Acylimidazoles were recognized in the early 1950s as reactive intermediates suitable for the acylation of amino compounds. The search for better coupling reagents than DCC led to the development of...
Matthias Junkers
Aldrich ChemFiles 2007, 7.2, 7.
Keywords: Acylations, Chemfiles, Esterifications, Peptide synthesis, Search

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COMU – Safer and More Efficient Peptide Coupling Reagent

Peptide synthesis relies heavily on efficient and reliable coupling reagents. A low tendency for racemization is a key requirement. This is especially true for solid phase peptide synthesis—quantitat...
Keywords: Building blocks, Calorimetry, Catalog, Condensations, Coupling reactions, Epimerizations, Methods, PEGylations, Peptide synthesis, Protocols, Racemizations, Search, Solid phase peptide synthesis, Solvents, Tools

Peer-Reviewed Papers
15

References

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