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538795 Aldrich

2-Trifluoromethyl-2-propanol

96%

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Properties

Related Categories Alcohols, Building Blocks, C2 to C6, Chemical Synthesis, Organic Building Blocks,
InChI Key   OCGWWLDZAFOHGD-UHFFFAOYSA-N
assay   96%
refractive index   n20/D 1.3335(lit.)
bp   83 °C(lit.)
density   1.17 g/mL at 25 °C(lit.)

Description

Packaging

5 g in glass bottle

Application

2-Trifluoromethyl-2-propanol may be employed as a solvent for the preparation of [18F]fluorothymidine. It may also be used in the synthesis of [2-(trifluoromethyl)-2-propyl nitrate] through nitration in nitric acid/trifluoroacetic anhydride.

General description

2-Trifluoromethyl-2-propanol is a fluorinated aliphatic alcohol. It can be prepared by reacting methyllithium, trifluoroacetone and trifluorovinyl bromide in ether. This can also be synthesized from the reaction between methylmagnesium bromide and 1,1,1-trifluoroacetone in ether.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS02  GHS02
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1987BE 3 / PGII
WGK Germany 
3
Flash Point(F) 
59 °F
Flash Point(C) 
15 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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