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540382 Aldrich

Bis-Boc-thiopseudourea, polymer-bound

100-200 mesh, extent of labeling: ~1.0 mmol/g S loading, 1 % cross-linked

Synonym: N,N′-Di-Boc-isothiouronium-methyl polystyrene

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Properties

Related Categories Chemical Synthesis, Other Supported Reagents, Solid Supported Synthesis, Specialty Synthesis, Supported Reagents More...
crosslinking   1 % cross-linked
extent of labeling   ~1.0 mmol/g S loading
particle size   100-200 mesh
storage temp.   2-8°C

Description

Application

This resin has been utilized in the synthesis of substituted guanidines.

Packaging

5, 25 g in glass bottle

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Guanylation of Amines by Bis(tert-butoxycarbonyl)thiopseudourea, Polymer-Bound

The synthesis of guanidine-containing bioactive molecules is of great interest in medicinal chemistry. The guanidine moiety is fully protonated under physiological conditions due to its strong basici...
Chemfiles Volume 5 Article 11
Keywords: Chromatography, Flash chromatography, Mass spectrometry, Medicinal chemistry, Methods, Nuclear magnetic resonance spectroscopy

Peer-Reviewed Papers
15

References

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