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543322 Aldrich

2-Phenylindole-3-carboxaldehyde

97%

Synonym: 3-Formyl-2-phenylindole

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Properties

Related Categories Aldehydes, Building Blocks, C13 to C27, C13-C60, Carbonyl Compounds,
InChI Key   IFIFXODAHZPTEY-UHFFFAOYSA-N
assay   97%
mp   249-253 °C(lit.)

Description

Packaging

5 g in glass bottle

Application

2-Phenylindole-3-carboxaldehyde may be used to synthesize:
• 2-phenylindole-3-carboxaldehyde oxime
• 2-phenyl-1H-indole-3-carboxaldehyde O-methyl oxime
• 2-phenylindole-3-carbonitrile

Reactant for preparation of:
• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Pyrimidinones via Biginelli reaction as antimicrobial agents
• [(phenyl)pyrazolyl]indole derivatives as antiinflammatory agents and analgesics
• Indole thiophene chalcones via Claisen-Schmidt condensation as antimicrobial and antioxidant agents
• Benzofuranone attached indole derivatives as PI3K inhibitors
• Ionone-based chalcones as novel antiandrogens
• Oxazolylindoles as antiinflammatory agents for edema

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Indoles

Sigma-Aldrich is proud to offer a new series of ChemFiles—called Privileged Structures, to our Drug Discovery and Organic Synthesis customers. Each piece will highlight a specific motif, selected app...
Chemfiles Volume 4 Article 8
Keywords: Applications, Building blocks, Cardiovascular, Chemfiles, Company, Diabetes, Diseases, Drug discovery, Medicinal chemistry, Organic synthesis, Respiratory

Peer-Reviewed Papers
15

References

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