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551163 Aldrich

Diethyl (2-cyanoethyl)phosphonate

95%

Synonym: (2-Cyanoethyl)-phosphonic acid diethyl ester, 3-(Diethylphosphono)propionitrile, NSC 43781, NSC 74863

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Properties

Related Categories C-C Bond Formation, Chemical Synthesis, Horner-Wadsworth-Emmons Reagents, Olefination, Synthetic Reagents More...
InChI Key   LDOZIDLMPNCNDI-UHFFFAOYSA-N
assay   95%
refractive index   n20/D 1.4380(lit.)
bp   110 °C/0.1 mmHg(lit.)
density   1.08 g/mL at 25 °C(lit.)

Description

Packaging

5 g in glass bottle

Application

Reactant for:
• Heteroatom-directed alkyl cyanation of alkynes
• Use as a fluorescent substrate for carbon-phosphorous lyase
• Microwave-assisted cleavage of phosphate, phosphonate, and phorphoramide esters
• Amination and stereoselective olefination for synthesis of HIV-1 antivirals


Reactant for synthesis of:
• Base-catalyzed stereospecific anti-Markovnikov addition reactants
• Lipophilic oxoamides with activity against phospholipase A2
• Triose phosphate isomerase of muscle inhibitors

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
KI6650000
Protocols & Articles
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